SCHEMBL48270

SCHEMBL48270

CCOC(=O)CNC(C)=O

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 3/20 0.59
MGAM O43451 1/20 0.56
SI P14410 1/20 0.56
MGAM2 Q2M2H8 1/20 0.56
PPID Q08752 3/20 0.49
ALDH1A1 P00352 6/20 0.48
SMN1; SMN2 Q16637 2/20 0.47
TRPA1 O75762 1/20 0.46
TSHR P16473 1/20 0.46
MAPT P10636 1/20 0.46
LMNA P02545 1/20 0.46
HSD17B10 Q99714 1/20 0.46
NPC1 O15118 1/20 0.45
RAB9A P51151 1/20 0.45
HPGD P15428 1/20 0.45
PPIB P23284 1/20 0.45
PPIA P62937 1/20 0.45
PPIG Q13427 1/20 0.45
SOAT1 P35610 1/20 0.44
PKM P14618 2/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Thiophene SCHEMBL27904832 0.85 GAA (0.46) GAAMGAMSIMGAM2PPID
SCHEMBL3267070 0.84 PPID (0.52) GAAMGAMSIMGAM2PPID
Toluene SCHEMBL28067808 0.84 PPID (0.59) GAAPPIDALDH1A1SMN1; SMN2LMNA
SCHEMBL7089973 0.83 GAA (0.61) GAAMGAMSIMGAM2PPID
SCHEMBL7946756 0.83 PPID (0.62) GAAMGAMSIMGAM2PPID
SCHEMBL24112258 0.82 GAA (0.55) GAAMGAMSIMGAM2PPID
SCHEMBL13809612 0.82 GAA (0.55) GAAMGAMSIMGAM2PPID
SCHEMBL5208480 0.82 GAA (0.41) GAAMGAMSIMGAM2PPID
SCHEMBL12809808 0.82 GAA (0.55) GAAMGAMSIMGAM2PPID
SCHEMBL10402670 0.82 GAA (0.41) GAAMGAMSIMGAM2PPID

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 313 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118620682-A Environment-friendly titanium alloy cutting fluid and preparation method thereof 河北思瑞恩新材料科技有限公司 2024-09-10 CN claimed
CN-105622518-B A kind of preparation method of 1H- imidazoles -4- formic acid 苏州艾缇克药物化学有限公司 2019-05-03 CN claimed
EP-3335720-A1 C-DI-GMP BINDING PEPTIDES Universität Basel (CH) 2018-06-20 EP claimed
CN-107987092-A Benzimidazole and thiazole acetamides and its application 沈阳药科大学 2018-05-04 CN claimed
CN-106431959-A Synthesis method of imidazole carboxylate drug intermediate ethyl acetamidoacetate 厦门莱恩斯特信息科技有限公司 2017-02-22 CN claimed
CN-105693619-A Method for catalytically synthesizing 1H-imidazole-4-carboxylic acid through inorganic-salt composite catalyst 苏州艾缇克药物化学有限公司 2016-06-22 CN claimed
CN-105646270-A Synthesis method of imidazole carboxylate pharmaceutical intermediate ethyl acetamidoacetate 成都东电艾尔科技有限公司 2016-06-08 CN claimed
CN-105622518-A Preparation method of 1H-imidazole-4-carboxylic acid ITIC MEDCHEM CO LTD 2016-06-01 CN claimed
CN-102643237-B Method for preparing 1H-imidazole-4-formic acid UNIV WUHAN TECH 2014-12-03 CN claimed
CN-102643237-A Method for preparing 1H-imidazole-4-formic acid UNIV WUHAN TECH 2012-08-22 CN claimed
CN-101563312-A Process for producing intermediate of asenapine synthesis SUMITOMO CHEMICAL CO (JP) 2009-10-21 CN claimed
US-20060251597-A1 ANTI-ODOR COMPOSITIONS AND THERAPEUTIC USE YU RUEY J 2006-11-09 US claimed
WO-2006119283-A2 ANTI-ODOR COMPOSITIONS AND THERAPEUTIC USE YU RUEY J (US) 2006-11-09 WO claimed
US-5677324-A MUSCLE RELAXANTS PFIZER INC. (US) 1997-10-14 US claimed
EP-0690855-B1 BENZOPYRANES AS POTASSIUM CHANNEL OPENERS PFIZER LTD (GB) 1996-12-18 EP claimed
EP-0690855-A1 BENZOPYRANES AS POTASSIUM CHANNEL OPENERS PFIZER LTD (GB) 1996-01-10 EP claimed
WO-1994020491-A1 BENZOPYRANES AS POTASSIUM CHANNEL OPENERS PFIZER LIMITED (GB) 1994-09-15 WO claimed
EP-0409413-B1 Diaryl ether heterocycles ICI PLC (GB) 1994-08-03 EP claimed
US-5208259-A Lipoxygenase enzyme inhibitors IMPERIAL CHEMICAL INDUSTRIES (GB) 1993-05-04 US claimed
EP-0409413-A2 Diaryl ether heterocycles IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1991-01-23 EP claimed