Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPID | Q08752 | 3/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.46 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | PPIB | P23284 | 1/20 | 0.46 |
| ▸ | PPIA | P62937 | 1/20 | 0.46 |
| ▸ | PPIG | Q13427 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL48270 | 0.84 | GAA (0.59) | PPIDALDH1A1KDM4EHPGDSMN1; SMN2 | |
| Toluene SCHEMBL8882403 | 0.81 | GAA (0.50) | PPIDALDH1A1RECQLSMN1; SMN2NPC1 | |
| Toluene SCHEMBL9479143 | 0.79 | GAA (0.52) | PPIDALDH1A1SMN1; SMN2NPC1RAB9A | |
| Ethyl Propionate SCHEMBL27658259 | 0.78 | MEN1 (0.52) | PPIDALDH1A1SMN1; SMN2NPC1LMNA | |
| SCHEMBL1221369 | 0.78 | RAB9A (0.66) | PPIDALDH1A1KDM4EPOLBHPGD | |
| SCHEMBL5966244 | 0.78 | ALDH1A1 (0.59) | PPIDALDH1A1HPGDSMN1; SMN2RAB9A | |
| Thiophene SCHEMBL27904832 | 0.78 | GAA (0.46) | PPIDALDH1A1KDM4EPOLBHPGD | |
| Malonic Acid Diethyl Ester SCHEMBL28691891 | 0.77 | GAA (0.56) | PPIDALDH1A1SMN1; SMN2NPC1RAB9A | |
| Toluene SCHEMBL9811805 | 0.77 | CYP4F2 (0.50) | PPIDALDH1A1SMN1; SMN2NPC1LMNA | |
| Acetoacetic Acid SCHEMBL9091733 | 0.77 | GAA (0.45) | PPIDALDH1A1RECQLSMN1; SMN2RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105622518-B | A kind of preparation method of 1H- imidazoles -4- formic acid | 苏州艾缇克药物化学有限公司 | 2019-05-03 | — | — | CN | claimed |
| CN-105622518-A | Preparation method of 1H-imidazole-4-carboxylic acid | ITIC MEDCHEM CO LTD | 2016-06-01 | — | — | CN | claimed |
| CN-105622518-A | Preparation method of 1H-imidazole-4-carboxylic acid | ITIC MEDCHEM CO LTD | 2016-06-01 | — | — | CN | disclosed |