Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Trinitrophenol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.55 |
| ▸ | GPR35 | Q9HC97 | 5/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.54 |
| ▸ | HPGD | P15428 | 2/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.54 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | TTR | P02766 | 1/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.54 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.54 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.54 |
| ▸ | RECQL | P46063 | 1/20 | 0.54 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trinitrophenol SCHEMBL9640075 | 0.98 | ALDH1A1 (0.53) | ALDH1A1GPR35TDP1HPGDMAPK1 | |
| Trinitrophenol SCHEMBL1534168 | 0.98 | ALDH1A1 (0.53) | ALDH1A1GPR35TDP1HPGDMAPK1 | |
| Trinitrophenol SCHEMBL2218621 | 0.95 | ALDH1A1 (0.55) | ALDH1A1GPR35TDP1HPGDMAPK1 | |
| Trinitrophenol SCHEMBL1503374 | 0.95 | ALDH1A1 (0.55) | ALDH1A1GPR35TDP1HPGDMAPK1 | |
| Trinitrophenol SCHEMBL7161635 | 0.95 | ALDH1A1 (0.55) | ALDH1A1GPR35TDP1HPGDMAPK1 | |
| Trinitrophenol SCHEMBL1132384 | 0.95 | ALDH1A1 (0.55) | ALDH1A1GPR35TDP1HPGDMAPK1 | |
| Trinitrophenol SCHEMBL2197455 | 0.95 | ALDH1A1 (0.55) | ALDH1A1GPR35TDP1HPGDMAPK1 | |
| Trinitrophenol SCHEMBL597737 | 0.95 | ALDH1A1 (0.55) | ALDH1A1GPR35TDP1HPGDMAPK1 | |
| Trinitrophenol SCHEMBL11029128 | 0.95 | ALDH1A1 (0.55) | ALDH1A1GPR35TDP1HPGDMAPK1 | |
| Trinitrophenol SCHEMBL11746242 | 0.95 | ALDH1A1 (0.55) | ALDH1A1GPR35TDP1HPGDMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 715 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024210466-A1 | BONDING COMPOSITION FOR LOW-TEMPERATURE SINTERING | 대주전자재료 주식회사 | 2024-10-10 | — | — | WO | claimed |
| CN-116189958-B | Low-temperature conductive paste composition, low-temperature conductive paste, conductive coating, electrode and heterojunction solar cell | 河北光兴半导体技术有限公司 | 2024-09-10 | — | — | CN | claimed |
| CN-116841120-A | Composition for preparing ultraviolet-sensitive photoetching silver paste, and preparation method and application thereof | 河北光兴半导体技术有限公司 | 2023-10-03 | — | — | CN | claimed |
| CN-116606246-A | Silver complex antibacterial agent with aromatic amide structure-containing nitrogen heterocyclic derivative as ligand, and preparation method and application thereof | 烟台哈尔滨工程大学研究院 | 2023-08-18 | — | — | CN | claimed |
| CN-116189958-A | Low-temperature conductive paste composition, low-temperature conductive paste, conductive coating, electrode and heterojunction solar cell | 河北光兴半导体技术有限公司 | 2023-05-30 | — | — | CN | claimed |
| CN-113549107-B | Picric acid double-quaternary phosphonium salt, slow-release film material, and preparation method and application thereof | 华南农业大学 | 2022-03-22 | — | — | CN | claimed |
| CN-113549107-A | Picric acid double-quaternary phosphonium salt, slow-release film material, and preparation method and application thereof | 华南农业大学 | 2021-10-26 | — | — | CN | claimed |
| CN-108129385-B | Composite quaternary ammonium salt nonlinear optical crystalline material and preparation method thereof | 华南农业大学 | 2020-01-14 | — | — | CN | claimed |
| US-20180215931-A1 | ANTIMICROBIAL COATING COMPOSITION WITH IMPROVED YELLOWING RESISTANCE | DOW GLOBAL TECHNOLOGIES LLC (US) | 2018-08-02 | — | — | US | claimed |
| EP-3334469-A1 | ANTIMICROBIAL COATING COMPOSITION WITH IMPROVED YELLOWING RESISTANCE | Dow Global Technologies LLC (US) | 2018-06-20 | — | — | EP | claimed |
| CN-1364056-A | Pyrithione biocides enhanced by silver, copper, or zinc ions | ARCH CHEM INC (US) | 2002-08-14 | — | — | CN | claimed |
| EP-1189504-A1 | PYRITHIONE BIOCIDES ENHANCED BY SILVER, COPPER, OR ZINC IONS | Arch Chemicals, Inc. (US) | 2002-03-27 | — | — | EP | claimed |
| CN-1294519-A | Pharmaceutical composition containing a compound having an activity of promoting the absorption of an active ingredient | INPHARMA SA (CH) | 2001-05-09 | — | — | CN | claimed |
| EP-1073470-A1 | PHARMACEUTICAL COMPOSITIONS CONTAINING COMPOUNDS WITH ACTIVITY FOR THE ENHANCEMENT OF ABSORPTION OF ACTIVE INGREDIENTS | INPHARMA S.A. (CH) | 2001-02-07 | — | — | EP | claimed |
| WO-2001000021-A1 | PYRITHIONE BIOCIDES ENHANCED BY SILVER, COPPER, OR ZINC IONS | ARCH CHEMICALS, INC. (US) | 2001-01-04 | — | — | WO | claimed |
| WO-2000048636-A1 | PHARMACEUTICAL COMPOSITIONS CONTAINING COMPOUNDS WITH ACTIVITY FOR THE ENHANCEMENT OF ABSORPTION OF ACTIVE INGREDIENTS | INPHARMA S.A. (CH) | 2000-08-24 | — | — | WO | claimed |
| EP-0516184-B1 | Antimicrobial latex composition | UNITIKA LTD (JP) | 1996-08-28 | — | — | EP | claimed |
| EP-0516184-A1 | Antimicrobial latex composition | UNITIKA LTD. (JP) | 1992-12-02 | — | — | EP | claimed |
| US-4902503-A | Antimicrobial latex composition | UNITIKA LTD. (JP) | 1990-02-20 | — | — | US | claimed |
| EP-0318258-A2 | Antimicrobial latex composition | UNITIKA LTD. (JP) | 1989-05-31 | — | — | EP | claimed |