Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Trinitrophenol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.55 |
| ▸ | GPR35 | Q9HC97 | 5/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.54 |
| ▸ | HPGD | P15428 | 2/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.54 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | TTR | P02766 | 1/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.54 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.54 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.54 |
| ▸ | RECQL | P46063 | 1/20 | 0.54 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trinitrophenol SCHEMBL29129188 | 0.98 | ALDH1A1 (0.53) | ALDH1A1GPR35TDP1HPGDMAPK1 | |
| Trinitrophenol SCHEMBL11287140 | 0.98 | ALDH1A1 (0.53) | ALDH1A1GPR35TDP1HPGDMAPK1 | |
| Trinitrophenol SCHEMBL7161635 | 0.95 | ALDH1A1 (0.55) | ALDH1A1GPR35TDP1HPGDMAPK1 | |
| Trinitrophenol SCHEMBL11746242 | 0.95 | ALDH1A1 (0.55) | ALDH1A1GPR35TDP1HPGDMAPK1 | |
| Trinitrophenol SCHEMBL653352 | 0.95 | ALDH1A1 (0.55) | ALDH1A1GPR35TDP1HPGDMAPK1 | |
| Trinitrophenol SCHEMBL1503374 | 0.95 | ALDH1A1 (0.55) | ALDH1A1GPR35TDP1HPGDMAPK1 | |
| Trinitrophenol SCHEMBL11029128 | 0.95 | ALDH1A1 (0.55) | ALDH1A1GPR35TDP1HPGDMAPK1 | |
| Trinitrophenol SCHEMBL597737 | 0.95 | ALDH1A1 (0.55) | ALDH1A1GPR35TDP1HPGDMAPK1 | |
| Trinitrophenol SCHEMBL48278 | 0.95 | ALDH1A1 (0.55) | ALDH1A1GPR35TDP1HPGDMAPK1 | |
| Trinitrophenol SCHEMBL2218621 | 0.95 | ALDH1A1 (0.55) | ALDH1A1GPR35TDP1HPGDMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 280 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119144906-B | 5200 MPa-grade steel wire, hot rolled wire rod and production method of wire rod | 江苏省沙钢钢铁研究院有限公司 | 2025-03-25 | — | — | CN | claimed |
| CN-119144906-A | 5200 MPa-grade steel wire, hot rolled wire rod and production method of wire rod | 江苏省沙钢钢铁研究院有限公司 | 2024-12-17 | — | — | CN | claimed |
| CN-115791348-A | Metallographic corrosive agent for aluminum alloy and use method | 中建安装集团有限公司 | 2023-03-14 | — | — | CN | claimed |
| CN-115528224-A | Positive plate of sodium ion battery and sodium ion battery | 浙江吉利动力总成有限公司 | 2022-12-27 | — | — | CN | claimed |
| CN-111508710-B | Electrolyte for wide-temperature aluminum electrolytic capacitor and preparation method thereof | 南通瑞泰电子有限公司 | 2022-01-18 | — | — | CN | claimed |
| CN-112268902-A | Detection method of cord steel GBC | 南京钢铁股份有限公司 | 2021-01-26 | — | — | CN | claimed |
| CN-108020493-B | High-silicon high-carbon steel wire rod austenite grain size measuring method | 江苏省沙钢钢铁研究院有限公司 | 2020-08-11 | — | — | CN | claimed |
| CN-111508710-A | Electrolyte for wide-temperature aluminum electrolytic capacitor and preparation method thereof | 南通瑞泰电子有限公司 | 2020-08-07 | — | — | CN | claimed |
| CN-107936064-B | Ferrocene triazole ionic nitrogen-rich energetic metal complex and preparation method thereof | 陕西师范大学 | 2020-05-29 | — | — | CN | claimed |
| CN-109988069-A | A kind of preparation method of potassium picrate | 山西壶化集团股份有限公司 | 2019-07-09 | — | — | CN | claimed |
| CN-106831889-A | Biferrocene Triazole ligand and its ionic type metal complex and preparation method | 陕西师范大学 | 2017-06-13 | — | — | CN | claimed |
| CN-106082324-A | A kind of iron-free Zr (SO4)2production method | 辽宁石化职业技术学院 | 2016-11-09 | — | — | CN | claimed |
| CN-102374990-A | Network carbide rating method of wire rod for prestressed steel stranded wire | TIANJIN ROCKCHECK STEEL GROUP CO LTD | 2012-03-14 | — | — | CN | claimed |
| CN-100368793-C | Method for detecting net type carbide of bearing semi-finished product by annealing corroding method | WAFANGDIAN BEARING GROUP CO (CN) | 2008-02-13 | — | — | CN | claimed |
| CN-1300070-C | Method for preparing burster of double salt of spherical alkali type lead picrate and azide lead | NANJING UNIVERSITY OF TECHNOLOGY (CN) | 2007-02-14 | — | — | CN | claimed |
| CN-1727315-A | Method for preparing burster of double salt of spherical alkali type lead picrate and azide lead | NANJING UNIVERSITY OF TECHNOLOGY (CN) | 2006-02-01 | — | — | CN | claimed |
| CN-1616952-A | Method for detecting net type carbide of bearing semi-finished product by annealing corroding method | WAFANGDIAN BEARING GROUP CO (CN) | 2005-05-18 | — | — | CN | claimed |
| US-4455150-A | Chemically enhanced combustion of water-slurry fuels | OLEN KENNETH R | 1984-06-19 | — | — | US | claimed |
| US-4159193-A | PAPER COMPRISING ACTIVATED ION EXCHANGE RESINS AND SILICA GEL ACTIVATED BY DEHYDRATION | I.N.R.S., Institut National de Recherche et de Securite pour la Prevention des Accidents du travail et des Maladies Professionnelles (FR) | 1979-06-26 | — | — | US | claimed |
| US-4050895-A | Optical analytical device, waveguide and method | MONSANTO RESEARCH CORPORATION (US) | 1977-09-27 | — | — | US | claimed |