Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AQP1 | P29972 | 3/20 | 0.42 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.32 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.31 |
| ▸ | EZH2 | Q15910 | 1/20 | 0.31 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.31 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.31 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.31 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.31 |
| ▸ | PRKAG3 | Q9UGI9 | 1/20 | 0.31 |
| ▸ | PRKAG2 | Q9UGJ0 | 1/20 | 0.31 |
| ▸ | PRKAB1 | Q9Y478 | 1/20 | 0.31 |
| ▸ | SIRT2 | Q8IXJ6 | 2/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
| ▸ | ICMT | O60725 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4768198 | 0.83 | AQP1 (0.42) | AQP1NUDT1EZH2PRKAB2PRKAG1 | |
| SCHEMBL4963529 | 0.80 | AQP1 (0.50) | AQP1NUDT1EZH2PRKAB2PRKAG1 | |
| SCHEMBL5140857 | 0.76 | AQP1 (0.42) | AQP1EZH2SIRT2 | |
| SCHEMBL4235651 | 0.76 | AQP1 (0.45) | AQP1EZH2PRKAB2PRKAG1PRKAA2 | |
| SCHEMBL4235648 | 0.74 | AQP1 (0.60) | AQP1EZH2 | |
| SCHEMBL4595484 | 0.73 | AQP1 (0.51) | AQP1EZH2SIRT2 | |
| SCHEMBL4226327 | 0.73 | AQP1 (0.55) | AQP1EZH2PRKAB2PRKAG1PRKAA2 | |
| SCHEMBL4768274 | 0.72 | AQP1 (0.57) | AQP1EZH2PRKAB2PRKAG1PRKAA2 | |
| SCHEMBL4225698 | 0.71 | AQP1 (0.54) | AQP1EZH2PRKAB2PRKAG1PRKAA2 | |
| SCHEMBL4230140 | 0.71 | AQP1 (0.45) | AQP1EZH2PRKAB2PRKAG1PRKAA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1874292-A2 | METHODS FOR MODULATING BLADDER FUNCTION | Wyeth (US) | 2008-01-09 | — | — | EP | disclosed |
| WO-2006116169-A2 | METHODS FOR MODULATING BLADDER FUNCTION | WYETH (US) | 2006-11-02 | — | — | WO | disclosed |