Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 4/20 | 0.41 |
| ▸ | HSP90AB1 | P08238 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | G6PD | P11413 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | CASP1 | P29466 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | AMD1 | P17707 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1704969 | 0.89 | HSP90AA1 (0.47) | HSP90AA1HSP90AB1ALDH1A1KDM4EMAPT | |
| SCHEMBL4829296 | 0.79 | S1PR4 (0.39) | MAPTCYP1A2HCRTR1HCRTR2CYP2C19 | |
| SCHEMBL6475032 | 0.76 | MAPT (0.36) | HSP90AA1HSP90AB1ALDH1A1KDM4EMAPT | |
| SCHEMBL1705138 | 0.75 | CYP1A2 (0.38) | ALDH1A1KDM4EKMT2ACYP1A2CYP2C9 | |
| SCHEMBL15716080 | 0.68 | TSHR (0.47) | ALDH1A1CASP1HSD17B10TSHRNUDT1 | |
| SCHEMBL21756757 | 0.67 | ALDH1A1 (0.42) | HSP90AA1HSP90AB1ALDH1A1KDM4EMAPT | |
| SCHEMBL15716606 | 0.67 | TRPV1 (0.40) | KDM4ETSHRSQORMBOAT4 | |
| SCHEMBL1705478 | 0.66 | CFTR (0.39) | HSP90AA1HSP90AB1ALDH1A1KDM4EMAPT | |
| SCHEMBL24226818 | 0.65 | TSHR (0.40) | ALDH1A1MAPTMEN1USP2KMT2A | |
| SCHEMBL13575846 | 0.64 | PIK3CA (0.41) | HSP90AA1HSP90AB1ALDH1A1KDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1627875-B1 | METHOD FOR PRODUCING CYCLIC DIAMINE DERIVATIVE OR SALT THEREOF | KOWA CO (JP) | 2013-07-31 | — | — | EP | disclosed |
| US-7459552-B2 | Method for producing cyclic diamine derivative or salt thereof | KOWA CO., LTD. (JP) | 2008-12-02 | — | — | US | disclosed |
| US-20060293519-A1 | Method for producing cyclic diamine derivative or salt thereof | KOWA CO., LTD. (JP) | 2006-12-28 | — | — | US | disclosed |
| EP-1627875-A1 | METHOD FOR PRODUCING CYCLIC DIAMINE DERIVATIVE OR SALT THEREOF | Kowa Co., Ltd. (JP) | 2006-02-22 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060293519-A1 | Method for producing cyclic diamine derivative or salt thereof | NNT, APRT, SAT1 | HSP90AA1 2612/4885HSP90AB1 2786/4885ALDH1A1 298/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.