Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR4 | O95977 | 9/20 | 0.39 |
| ▸ | CFTR | P13569 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.33 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | MPI | P34949 | 2/20 | 0.33 |
| ▸ | PHOSPHO1 | Q8TCT1 | 2/20 | 0.33 |
| ▸ | PMM2 | O15305 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1705478 | 0.90 | CFTR (0.39) | S1PR4CFTRCNR2HCRTR1HCRTR2 | |
| SCHEMBL6475032 | 0.83 | MAPT (0.36) | S1PR4CFTRMPIPHOSPHO1PMM2 | |
| SCHEMBL6472524 | 0.81 | MPI (0.37) | S1PR4CFTRNPC1CNR2MPI | |
| SCHEMBL4829264 | 0.79 | HSP90AA1 (0.41) | CNR2HCRTR1HCRTR2CYP1A2CYP2C19 | |
| SCHEMBL4829348 | 0.75 | S1PR4 (0.39) | S1PR4NPC1RAB9ASMN1; SMN2MAPT | |
| SCHEMBL4833523 | 0.74 | TSHR (0.34) | S1PR4NPC1RAB9ASMN1; SMN2MAPT | |
| SCHEMBL1705138 | 0.73 | CYP1A2 (0.38) | SMN1; SMN2CNR2HCRTR1HCRTR2CYP1A2 | |
| SCHEMBL8808836 | 0.69 | LMNA (0.46) | SMN1; SMN2CYP3A4MAPTLMNA | |
| SCHEMBL3715523 | 0.69 | MPI (0.43) | S1PR4CFTRSMN1; SMN2CYP3A4MPI | |
| SCHEMBL15716302 | 0.67 | NPC1 (0.46) | S1PR4NPC1RAB9ASMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1627875-B1 | METHOD FOR PRODUCING CYCLIC DIAMINE DERIVATIVE OR SALT THEREOF | KOWA CO (JP) | 2013-07-31 | — | — | EP | disclosed |
| US-7459552-B2 | Method for producing cyclic diamine derivative or salt thereof | KOWA CO., LTD. (JP) | 2008-12-02 | — | — | US | disclosed |
| US-20060293519-A1 | Method for producing cyclic diamine derivative or salt thereof | KOWA CO., LTD. (JP) | 2006-12-28 | — | — | US | disclosed |
| EP-1627875-A1 | METHOD FOR PRODUCING CYCLIC DIAMINE DERIVATIVE OR SALT THEREOF | Kowa Co., Ltd. (JP) | 2006-02-22 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060293519-A1 | Method for producing cyclic diamine derivative or salt thereof | NNT, APRT, SAT1 | S1PR4 1248/4885CFTR 4144/4885NPC1 1124/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.