Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.36 |
| ▸ | KCNA5 | P22460 | 4/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.35 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4506878 | 0.93 | KDM4E (0.42) | KDM4ELMNAHSD17B10HPGDALDH1A1 | |
| SCHEMBL6727040 | 0.83 | LMNA (0.44) | KDM4ELMNAHSD17B10HPGDALDH1A1 | |
| SCHEMBL14503005 | 0.82 | ALOX15 (0.50) | KDM4ELMNAHSD17B10HPGDALDH1A1 | |
| SCHEMBL1704603 | 0.81 | SOAT1 (0.58) | LMNAALDH1A1TSHRSOAT1 | |
| SCHEMBL1705138 | 0.81 | CYP1A2 (0.38) | KDM4EHPGDALDH1A1CYP1A2 | |
| Hydrochloric Acid SCHEMBL6474056 | 0.81 | SOAT1 (0.58) | LMNAALDH1A1TSHRSOAT1 | |
| SCHEMBL4514770 | 0.79 | LMNA (0.54) | KDM4ELMNAHSD17B10HPGDALDH1A1 | |
| SCHEMBL4532301 | 0.74 | LMNA (0.44) | KDM4ELMNAHSD17B10HPGDALDH1A1 | |
| SCHEMBL1704605 | 0.74 | SOAT1 (0.51) | KDM4EHSD17B10HPGDALDH1A1TSHR | |
| Hydrochloric Acid SCHEMBL1704617 | 0.73 | SOAT1 (0.51) | KDM4EHSD17B10HPGDALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1627875-B1 | METHOD FOR PRODUCING CYCLIC DIAMINE DERIVATIVE OR SALT THEREOF | KOWA CO (JP) | 2013-07-31 | — | — | EP | disclosed |
| US-7459552-B2 | Method for producing cyclic diamine derivative or salt thereof | KOWA CO., LTD. (JP) | 2008-12-02 | — | — | US | disclosed |
| US-20060293519-A1 | Method for producing cyclic diamine derivative or salt thereof | KOWA CO., LTD. (JP) | 2006-12-28 | — | — | US | disclosed |
| EP-1627875-A1 | METHOD FOR PRODUCING CYCLIC DIAMINE DERIVATIVE OR SALT THEREOF | Kowa Co., Ltd. (JP) | 2006-02-22 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060293519-A1 | Method for producing cyclic diamine derivative or salt thereof | NNT, APRT, SAT1 | KDM4E 795/4885LMNA 4263/4885HSD17B10 1273/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.