SCHEMBL4829700

SCHEMBL4829700

Nc1cc(N)c(-n2ccnc2)cc1N

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
IDO1 P14902 4/20 0.61
LMNA P02545 2/20 0.47
MAPT P10636 2/20 0.47
CYP3A4 P08684 5/20 0.42
CYP1A2 P05177 3/20 0.42
CYP2D6 P10635 3/20 0.42
CYP2C9 P11712 3/20 0.42
CYP2C19 P33261 3/20 0.42
GAA P10253 1/20 0.42
MEN1 O00255 1/20 0.41
ALDH1A1 P00352 1/20 0.41
MAPK1 P28482 1/20 0.41
PMP22 Q01453 1/20 0.41
KMT2A Q03164 1/20 0.41
TDP1 Q9NUW8 1/20 0.41
CYP19A1 P11511 2/20 0.40
CYP11B1 P15538 2/20 0.40
CYP11B2 P19099 2/20 0.40
LOXL2 Q9Y4K0 1/20 0.39
ENPP2 Q13822 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8059739 0.82 IDO1 (0.51) IDO1LMNAMAPTCYP3A4CYP1A2
SCHEMBL16672827 0.77 IDO1 (0.54) IDO1LMNAMAPTCYP3A4CYP1A2
SCHEMBL997561 0.76 IDO1 (0.53) IDO1LMNAMAPTCYP3A4CYP1A2
SCHEMBL1239654 0.76 IDO1 (0.53) IDO1LMNAMAPTCYP3A4CYP1A2
SCHEMBL3284515 0.76 IDO1 (0.53) IDO1LMNAMAPTCYP3A4CYP1A2
SCHEMBL23486498 0.76 IDO1 (0.76) IDO1LMNAMAPTCYP3A4CYP1A2
SCHEMBL13242920 0.76 IDO1 (0.66) IDO1LMNAMAPTCYP3A4CYP1A2
SCHEMBL14067619 0.76 ENPP2 (0.53) IDO1LMNAMAPTCYP3A4CYP1A2
SCHEMBL29758190 0.76 IDO1 (0.76) IDO1LMNAMAPTCYP3A4CYP1A2
SCHEMBL25822705 0.76 IDO1 (0.66) IDO1LMNAMAPTCYP3A4CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 58 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7291429-B2 Naphthalenetetracarboxylic acid diimide derivatives and electrophotographic photoconductive material using the derivatives SAMSUNG ELECTRONICS CO., LTD. (KR) 2007-11-06 US claimed
US-20050112482-A1 Naphthalenetetracarboxylic acid diimide derivatives and electrophotographic photoconductive material using the derivatives SAMSUNG ELECTRONICS CO., LTD. (KR) 2005-05-26 US claimed
EP-1111479-B1 METHOD AND APPARATUS FOR IMAGE FORMATION TORAY ENG CO LTD (JP) 2012-06-20 EP disclosed
US-7341811-B2 Electrophotographic photoreceptor using the electron transferring compound SAMSUNG ELECTRONICS CO., LTD. (KR) 2008-03-11 US disclosed
US-7314692-B2 Phenylazomethylene-cyclohexadienone derivatives comprising electron withdrawing group and electrophotographic photoreceptor comprising the derivatives SAMSUNG ELECTRONICS CO., LTD. (KR) 2008-01-01 US disclosed
US-7291429-B2 Naphthalenetetracarboxylic acid diimide derivatives and electrophotographic photoconductive material using the derivatives SAMSUNG ELECTRONICS CO., LTD. (KR) 2007-11-06 US disclosed
US-7157196-B2 Containing charge generating compound and charge transfer compound SAMSUNG ELECTRONICS CO., LTD. (KR) 2007-01-02 US disclosed
US-20050130051-A1 Phenylazomethylene-cyclohexadienone derivatives comprising electron withdrawing group and electrophotographic photoreceptor comprising the derivatives SAMSUNG ELECTRONICS CO., LTD. (KR) 2005-06-16 US disclosed
US-20050118519-A1 Electron transferring compound and electrophotographic photoreceptor using the electron transferring compound S-PRINTING SOLUTION CO., LTD. (KR) 2005-06-02 US disclosed
US-20050112482-A1 Naphthalenetetracarboxylic acid diimide derivatives and electrophotographic photoconductive material using the derivatives SAMSUNG ELECTRONICS CO., LTD. (KR) 2005-05-26 US disclosed
US-20050003286-A1 Naphthalenetetracarboxylic acid diimide derivatives and electrophotographic photoconductive material having the same SAMSUNG ELECTRONICS CO., LTD (KR) 2005-01-06 US disclosed
US-4480019-A AROMATIC DISAZO PIGMENT MITA INDUSTRIAL CO., LTD. (JP) 1984-10-30 US disclosed
US-4447513-A A TETRAKIS-AZO PIGMENT MITA INDUSTRIAL CO., LTD. (JP) 1984-05-08 US disclosed
US-4433039-A ELECTROCONDUCTIVE SUBSTRATE WITH PHOTOSENSITIVE LAYER CONTAINING CHARGE TRANSFER COMPOUND MITA INDUSTRIAL CO. LTD. (JP) 1984-02-21 US disclosed
EP-0098089-A2 Electrophotographic photosensitive material MITA INDUSTRIAL CO. LTD. (JP) 1984-01-11 EP disclosed
EP-0094079-A1 Photosensitive material for electrophotography MITA INDUSTRIAL CO. LTD. (JP) 1983-11-16 EP disclosed
EP-0091833-A1 Electrophotographic photosensitive material MITA INDUSTRIAL CO. LTD. (JP) 1983-10-19 EP disclosed
EP-0085465-A1 Photosensitive material for electrophotography MITA INDUSTRIAL CO. LTD. (JP) 1983-08-10 EP disclosed
EP-0078575-A1 An electrophotographic photosensitive material MITA INDUSTRIAL CO. LTD. (JP) 1983-05-11 EP disclosed
EP-0077593-A2 Photosensitive material for electrophotography MITA INDUSTRIAL CO. LTD. (JP) 1983-04-27 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050112482-A1 Naphthalenetetracarboxylic acid diimide derivatives and electrophotographic photoconductive material using the derivatives ADSL, DCLK1, DCLK2 IDO1 1214/4885LMNA 383/4885MAPT 4287/4885
US-20050003286-A1 Naphthalenetetracarboxylic acid diimide derivatives and electrophotographic photoconductive material having the same CCNL2, ADSL, F10 IDO1 772/4885LMNA 320/4885MAPT 4284/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.