Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.67 |
| ▸ | MEN1 | O00255 | 2/20 | 0.67 |
| ▸ | MAPT | P10636 | 2/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.67 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.67 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.67 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.67 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.67 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.67 |
| ▸ | HTR2B | P41595 | 1/20 | 0.67 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.67 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.67 |
| ▸ | HTT | P42858 | 1/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | HTR1A | P08908 | 4/20 | 0.48 |
| ▸ | PARP1 | P09874 | 2/20 | 0.48 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.47 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.46 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Exalamide SCHEMBL27702423 | 0.80 | LMNA (1.00) | LMNAMEN1MAPTKMT2ANR1I2 | |
| SCHEMBL29627441 | 0.80 | LMNA (1.00) | LMNAMEN1MAPTKMT2ANR1I2 | |
| SCHEMBL874312 | 0.80 | LMNA (1.00) | LMNAMEN1MAPTKMT2ANR1I2 | |
| SCHEMBL4656110 | 0.80 | LMNA (1.00) | LMNAMEN1MAPTKMT2ANR1I2 | |
| Exalamide SCHEMBL151112 | 0.80 | LMNA (1.00) | LMNAMEN1MAPTKMT2ANR1I2 | |
| SCHEMBL9417650 | 0.80 | LMNA (1.00) | LMNAMEN1MAPTKMT2ANR1I2 | |
| SCHEMBL29603307 | 0.80 | LMNA (1.00) | LMNAMEN1MAPTKMT2ANR1I2 | |
| SCHEMBL873025 | 0.80 | LMNA (1.00) | LMNAMEN1MAPTKMT2ANR1I2 | |
| SCHEMBL5147507 | 0.80 | LMNA (1.00) | LMNAMEN1MAPTKMT2ANR1I2 | |
| SCHEMBL5878814 | 0.80 | LMNA (1.00) | LMNAMEN1MAPTKMT2ANR1I2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1996180-A1 | ANTIBACTERIAL AGENTS | Prolysis Limited (GB) | 2008-12-03 | — | — | EP | disclosed |
| WO-2007107758-A1 | ANTIBACTERIAL AGENTS | PROLYSIS LTD (GB) | 2007-09-27 | — | — | WO | disclosed |