SCHEMBL873025

SCHEMBL873025

CCCCCCCCCCOc1ccccc1C(N)=O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 4/20 1.00
CYP3A4 P08684 2/20 1.00
MAPT P10636 2/20 1.00
MEN1 O00255 1/20 1.00
NR1I2 O75469 1/20 1.00
CHRM2 P08172 1/20 1.00
ADRA2A P08913 1/20 1.00
OPRK1 P41145 1/20 1.00
HTR2B P41595 1/20 1.00
SLC6A3 Q01959 1/20 1.00
KMT2A Q03164 1/20 1.00
HDAC6 Q9UBN7 1/20 1.00
HTT P42858 1/20 0.63
KDM4E B2RXH2 2/20 0.59
TSHR P16473 2/20 0.57
ALDH1A1 P00352 2/20 0.57
NPSR1 Q6W5P4 1/20 0.57
SMN1; SMN2 Q16637 1/20 0.56
PTPN11 Q06124 1/20 0.56
TP53 P04637 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5878814 1.00 LMNA (1.00) LMNACYP3A4MAPTMEN1NR1I2
Exalamide SCHEMBL27702423 1.00 LMNA (1.00) LMNACYP3A4MAPTMEN1NR1I2
SCHEMBL29603307 1.00 LMNA (1.00) LMNACYP3A4MAPTMEN1NR1I2
SCHEMBL874312 1.00 LMNA (1.00) LMNACYP3A4MAPTMEN1NR1I2
SCHEMBL5147507 1.00 LMNA (1.00) LMNACYP3A4MAPTMEN1NR1I2
Exalamide SCHEMBL151112 1.00 LMNA (1.00) LMNACYP3A4MAPTMEN1NR1I2
SCHEMBL9417650 1.00 LMNA (1.00) LMNACYP3A4MAPTMEN1NR1I2
SCHEMBL29627441 1.00 LMNA (1.00) LMNACYP3A4MAPTMEN1NR1I2
SCHEMBL4656110 1.00 LMNA (1.00) LMNACYP3A4MAPTMEN1NR1I2
SCHEMBL7649315 1.00 LMNA (1.00) LMNACYP3A4MAPTMEN1NR1I2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 602 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4110277-B1 COMPOSITIONS COMPRISING (BIO)-ALKANEDIOLS SYMRISE AG (DE) 2026-04-22 EP claimed
EP-4110276-B1 COMPOSITIONS COMPRISING ALKANEDIOLS SYMRISE AG (DE) 2026-01-28 EP claimed
EP-4477264-A2 COMPOSITIONS COMPRISING ONE OR MORE (BIO)-ALKANEDIOLS WITH ACTIVE INGREDIENTS Symrise AG (DE) 2024-12-18 EP claimed
US-20230293404-A1 Compositions Comprising Natural Polymers and One or More (Bio)-Alkanediols SYMRISE AG (DE) 2023-09-21 US claimed
EP-4103143-A1 COMPOSITIONS COMPRISING NATURAL POLYMERS AND ONE OR MORE (BIO)-ALKANEDIOLS Symrise AG (DE) 2022-12-21 EP claimed
WO-2022122132-A1 COMPOSITIONS COMPRISING NATURAL POLYMERS AND ONE OR MORE (BIO)-ALKANEDIOLS SYMRISE AG (DE) 2022-06-16 WO claimed
WO-2022122890-A1 COMPOSITIONS COMPRISING NATURAL POLYMERS AND ONE OR MORE (BIO)-ALKANEDIOLS SYMRISE AG (DE) 2022-06-16 WO claimed
EP-4103144-B1 COMPOSITIONS COMPRISING UV-FILTERS AND ONE OR MORE (BIO)-ALKANEDIOLS SYMRISE AG (DE) 2026-05-27 EP disclosed
EP-4110277-B1 COMPOSITIONS COMPRISING (BIO)-ALKANEDIOLS SYMRISE AG (DE) 2026-04-22 EP disclosed
US-20260096978-A1 A METHOD FOR PREVENTING, MITIGATING AND/OR TREATING PTGS2-INDUCED SKIN DISORDERS AND RELATED DYSFUNCTIONS SYMRISE AG (DE) 2026-04-09 US disclosed
US-20260047994-A1 AN ACTIVE COMPOSITION COMPRISING RETINOL SYMRISE AG (DE) 2026-02-19 US disclosed
EP-4110276-B1 COMPOSITIONS COMPRISING ALKANEDIOLS SYMRISE AG (DE) 2026-01-28 EP disclosed
EP-4340807-B1 HAIR COLOR COMPOSITIONS FOR MITIGATING COLOR LOSS LUBRIZOL ADVANCED MAT INC (US) 2026-01-28 EP disclosed
US-20030175366-A1 Plant Extracts and Methods of Treating Skin Therewith COGNIS FRANCE, S.A. (FR) 2003-09-18 US disclosed
US-20030170298-A1 Proliposomal encapsulated preparations COGNIS IBERIA S.L. (ES) 2003-09-11 US disclosed
US-20030161847-A1 Use of hydroxyethers in cosmetic and pharmaceutical preparations COGNIS IP MANAGEMENT GMBH (DE) 2003-08-28 US disclosed
US-20030138394-A1 Cosmetic and/or pharmaceutical preparations that contain an extract of the plant argania spinosa COGNIS FRANCE S.A. (FR) 2003-07-24 US disclosed
US-20030113354-A1 Granular solid with monodisperse particle size distribution COGNIS IP MANAGEMENT GMBH (DE) 2003-06-19 US disclosed
US-20030068364-A1 Pro-liposomal encapsulated preparations (iv) COGNIS IBERIA S.L (ES) 2003-04-10 US disclosed
US-20030064106-A1 Microcapsules-vi COGNIS IBERIA, S.L. (ES) 2003-04-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030113354-A1 Granular solid with monodisperse particle size distribution U2AF2, SDHA, SDHB LMNA 3160/4885CYP3A4 2354/4885MAPT 1079/4885
US-20030138394-A1 Cosmetic and/or pharmaceutical preparations that contain an extract of the plant argania spinosa ARG1, ARG2, CUTA LMNA 1498/4885CYP3A4 611/4885MAPT 1603/4885
US-20030064106-A1 Microcapsules-vi CHMP4B, LIPA, PHOSPHO1 LMNA 909/4885CYP3A4 3932/4885MAPT 2223/4885
US-20030161847-A1 Use of hydroxyethers in cosmetic and pharmaceutical preparations CYP8B1, SQLE, HSD17B7 LMNA 3554/4885CYP3A4 153/4885MAPT 2209/4885
US-20260047994-A1 AN ACTIVE COMPOSITION COMPRISING RETINOL RBP4, LRAT, RARB LMNA 2563/4885CYP3A4 2860/4885MAPT 781/4885
US-20030068364-A1 Pro-liposomal encapsulated preparations (iv) PHOSPHO1, LIPA, PLIN5 LMNA 125/4885CYP3A4 2170/4885MAPT 1456/4885
US-20230293404-A1 Compositions Comprising Natural Polymers and One or More (Bio)-Alkanediols ACMSD, CUTA, DDC LMNA 3696/4885CYP3A4 3177/4885MAPT 662/4885
US-20030170298-A1 Proliposomal encapsulated preparations LIPA, PLIN5, PNLIP LMNA 1888/4885CYP3A4 4432/4885MAPT 938/4885
US-20260096978-A1 A METHOD FOR PREVENTING, MITIGATING AND/OR TREATING PTGS2-INDUCED SKIN DISORDERS AND RELATED DYSFUNCTIONS PTGS2, PTGES2, PTGS1 LMNA 2747/4885CYP3A4 2277/4885MAPT 4406/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.