Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | TYR | P14679 | 1/20 | 0.44 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.40 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.40 |
| ▸ | SLC22A3 | O75751 | 1/20 | 0.40 |
| ▸ | KIF11 | P52732 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | BCHE | P06276 | 1/20 | 0.34 |
| ▸ | ACHE | P22303 | 1/20 | 0.34 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1093877 | 0.76 | TSHR (0.52) | TSHRLMNATYRSLC22A2SLC22A1 | |
| SCHEMBL424728 | 0.74 | TSHR (0.73) | TSHRLMNATYRSLC22A2SLC22A1 | |
| SCHEMBL13454805 | 0.74 | TSHR (0.50) | TSHRLMNATYRSLC22A2SLC22A1 | |
| SCHEMBL2154563 | 0.72 | TSHR (0.48) | TSHRLMNATYRSLC22A2SLC22A1 | |
| SCHEMBL2886665 | 0.72 | TSHR (0.48) | TSHRLMNATYRSLC22A2SLC22A1 | |
| SCHEMBL1305145 | 0.72 | TSHR (0.48) | TSHRLMNATYRSLC22A2SLC22A1 | |
| SCHEMBL1304647 | 0.72 | TSHR (0.48) | TSHRLMNATYRSLC22A2SLC22A1 | |
| SCHEMBL8384689 | 0.72 | LMNA (0.52) | TSHRLMNATYRSLC22A2SLC22A1 | |
| SCHEMBL2548631 | 0.72 | TSHR (0.48) | TSHRLMNATYRSLC22A2SLC22A1 | |
| SCHEMBL4830212 | 0.70 | TSHR (0.46) | TSHRLMNATYRSLC22A2SLC22A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7378537-B2 | Olefin oligomerization catalysts and methods of using same | CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) | 2008-05-27 | — | — | US | disclosed |
| US-20080027188-A1 | OLEFIN OLIGOMERIZATION CATALYSTS AND METHODS OF USING SAME | CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) | 2008-01-31 | — | — | US | disclosed |