SCHEMBL483080

SCHEMBL483080

COc1nc(C)nc(C(Br)(Br)Br)n1

nearest known ligand 0.37

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
GAA P10253 1/20 0.37
ALDH1A1 P00352 1/20 0.32
MEN1 O00255 1/20 0.31
MAPT P10636 1/20 0.31
TSHR P16473 1/20 0.31
KMT2A Q03164 1/20 0.31
ATM Q13315 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL82113 0.86 MEN1 (0.35) ALDH1A1MEN1MAPTTSHRKMT2A
SCHEMBL821298 0.78 GAA (0.37) GAA
SCHEMBL13012211 0.78 GAA (0.37) GAA
SCHEMBL79683 0.78
SCHEMBL1131131 0.75 GAA (0.47) GAAALDH1A1MEN1MAPTTSHR
SCHEMBL8844371 0.75 GAA (0.47) GAAALDH1A1MEN1MAPTTSHR
SCHEMBL483236 0.68 HSP90AB1 (0.41) ALDH1A1
SCHEMBL11785129 0.68 KDM4E (0.33)
SCHEMBL9759431 0.67 GAA (0.41) GAAALDH1A1MEN1MAPTTSHR
SCHEMBL8844365 0.65 GAA (0.44) GAAALDH1A1MEN1MAPTTSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1764650-B1 Photosensitive composition, and lithographic printing plate precursor and image-recording method using the same FUJIFILM CORP (JP) 2013-02-27 EP disclosed
EP-1288720-B1 Plate-making method of printing plate FUJIFILM CORP (JP) 2012-02-01 EP disclosed
EP-1744212-B1 Photosensitive composition FUJIFILM CORP (JP) 2012-01-11 EP disclosed
EP-1834765-A2 Lithographic printing plate precursor and method for preparation of lithographic printing plate FUJIFILM Corporation (JP) 2007-09-19 EP disclosed
US-20070212641-A1 Lithographic printing plate precursor and method for preparation of lithographic printing plate FUJIFILM CORPORATION (JP) 2007-09-13 US disclosed
EP-1764650-A1 Photosensitive composition, and lithographic printing plate precursor and image-recording method using the same FUJIFILM Corporation (JP) 2007-03-21 EP disclosed
US-7179582-B2 Radical polymerizable composition and lithographic printing plate precursor using the same FUJI PHOTO FILM CO., LTD. (JP) 2007-02-20 US disclosed
US-20070015087-A1 Photosensitive composition FUJI PHOTO FILM CO., LTD. 2007-01-18 US disclosed
EP-1744212-A2 Photosensitive composition Fuji Photo Film Co., Ltd. (JP) 2007-01-17 EP disclosed
CN-1896873-A Photosensitive composition FUJI PHOTO FILM CO LTD (JP) 2007-01-17 CN disclosed
EP-1238801-B1 Lithographic printing plate precursor FUJI PHOTO FILM CO LTD (JP) 2006-05-17 EP disclosed
US-6875557-B2 Photopolymerization; development using alkalinity developer FUJI PHOTO FILM CO., LTD. (JP) 2005-04-05 US disclosed
US-20050031986-A1 Radical polymerizable composition and lithographic printing plate precursor using the same FUJI PHOTO FILM CO., LTD. 2005-02-10 US disclosed
US-6818372-B2 FINE PARTICLES CONTAINING A RADICAL POLYMERIZABLE ENCAPSULATED BY MICROCAPSULES FUJI PHOTO FILM CO., LTD. (JP) 2004-11-16 US disclosed
US-20030190554-A1 Photopolymerization; development using alkalinity developer FUJIFILM CORPORATION (JP) 2003-10-09 US disclosed
US-20030084806-A1 FINE PARTICLES CONTAINING A RADICAL POLYMERIZABLE ENCAPSULATED BY MICROCAPSULES FUJIFILM CORPORATION (JP) 2003-05-08 US disclosed
EP-1288720-A1 Plate-making method of printing plate FUJI PHOTO FILM CO., LTD. (JP) 2003-03-05 EP disclosed
EP-1238801-A2 Lithographic printing plate precursor FUJI PHOTO FILM CO., LTD. (JP) 2002-09-11 EP disclosed