Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN1 | Q05586 | 6/20 | 0.49 |
| ▸ | GRIN2A | Q12879 | 6/20 | 0.49 |
| ▸ | GRIN2D | O15399 | 5/20 | 0.49 |
| ▸ | GRIN2C | Q14957 | 5/20 | 0.49 |
| ▸ | GRIN2B | Q13224 | 4/20 | 0.49 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.48 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.48 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.48 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.48 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.48 |
| ▸ | DRD4 | P21917 | 1/20 | 0.48 |
| ▸ | DRD3 | P35462 | 1/20 | 0.48 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.48 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.48 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.48 |
| ▸ | CACNA1S | Q13698 | 1/20 | 0.48 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.48 |
| ▸ | MRGPRX2 | Q96LB1 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | CRHBP | P24387 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8658460 | 0.79 | GRIN1 (0.55) | GRIN1GRIN2AGRIN2DGRIN2CGRIN2B | |
| SCHEMBL8660746 | 0.76 | GRIN1 (0.54) | GRIN1GRIN2AGRIN2DGRIN2CGRIN2B | |
| SCHEMBL8658397 | 0.75 | GRIN1 (0.51) | GRIN1GRIN2AGRIN2DGRIN2CGRIN2B | |
| SCHEMBL3166469 | 0.74 | GRIN1 (0.68) | GRIN1GRIN2AGRIN2DGRIN2CGRIN2B | |
| SCHEMBL8657476 | 0.74 | GRIN1 (0.50) | GRIN1GRIN2AGRIN2DGRIN2CGRIN2B | |
| SCHEMBL11034545 | 0.70 | KIF11 (0.48) | KCNH2CYP2D6CYP2C19 | |
| SCHEMBL8661640 | 0.70 | GRIN1 (0.48) | GRIN1GRIN2AGRIN2DGRIN2CGRIN2B | |
| SCHEMBL14975671 | 0.70 | GRIN1 (0.38) | GRIN1GRIN2AGRIN2DGRIN2CGRIN2B | |
| SCHEMBL7317845 | 0.69 | KCNN4 (0.41) | GRIN1GRIN2AGRIN2DGRIN2CGRIN2B | |
| SCHEMBL6264501 | 0.68 | GRIN1 (0.74) | GRIN1GRIN2AGRIN2DGRIN2CGRIN2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1993519-A2 | METHODS AND COMPOSITIONS FOR DETERRING ABUSE OF ORALLY ADMINISTERED PHARMACEUTICAL PRODUCTS | ACURA PHARMACEUTICALS, INC. (US) | 2008-11-26 | — | — | EP | disclosed |
| WO-2007106550-A2 | METHODS AND COMPOSITIONS FOR DETERRING ABUSE OF ORALLY ADMINISTERED PHARMACEUTICAL PRODUCTS | ACURA PHARMACEUTICALS, INC. (US) | 2007-09-20 | — | — | WO | disclosed |