Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR1A | P37288 | 18/20 | 0.81 |
| ▸ | OXTR | P30559 | 13/20 | 0.73 |
| ▸ | AVPR2 | P30518 | 9/20 | 0.73 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.64 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.64 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.64 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.64 |
| ▸ | DRD3 | P35462 | 1/20 | 0.64 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2130133 | 0.89 | AVPR1A (0.67) | AVPR1AOXTRAVPR2CHRM2CHRM4 | |
| SCHEMBL38949 | 0.89 | AVPR1A (0.81) | AVPR1AOXTRAVPR2CHRM2CHRM4 | |
| SCHEMBL4840202 | 0.88 | AVPR1A (0.91) | AVPR1AOXTRAVPR2CHRM2CHRM4 | |
| SCHEMBL6425099 | 0.88 | AVPR1A (0.88) | AVPR1AOXTRAVPR2CHRM2CHRM4 | |
| SCHEMBL2128549 | 0.88 | AVPR1A (0.62) | AVPR1AOXTRAVPR2CHRM2CHRM4 | |
| SCHEMBL45615 | 0.88 | AVPR1A (0.84) | AVPR1AOXTRAVPR2CHRM2CHRM4 | |
| Hydrochloric Acid SCHEMBL4829058 | 0.88 | AVPR1A (0.87) | AVPR1AOXTRAVPR2CHRM2CHRM4 | |
| SCHEMBL45440 | 0.87 | AVPR1A (0.83) | AVPR1AOXTRAVPR2CHRM2CHRM4 | |
| SCHEMBL4828970 | 0.87 | AVPR1A (0.80) | AVPR1AOXTRAVPR2CHRM2CHRM4 | |
| SCHEMBL38380 | 0.86 | AVPR1A (0.88) | AVPR1AOXTRAVPR2CHRM2CHRM4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080275026-A1 | Benzamide derivatives as oxytocin agonists and vasopressin antagonists | FERRING B.V. | 2008-11-06 | — | — | US | disclosed |
| US-7407949-B2 | Benzamide derivatives as oxytocin agonists and vasopressin antagonists | FERRING B.V. (NL) | 2008-08-05 | — | — | US | disclosed |
| US-20060166971-A1 | Benzamide derivatives as oxytocin agonists and vasopressin antagonists | FERRING B.V. (NL) | 2006-07-27 | — | — | US | disclosed |
| US-20050032777-A1 | Diazacycloalkanes as oxytocin agonists | FEERING B.V. (NL) | 2005-02-10 | — | — | US | disclosed |
| EP-1449844-A1 | benzamide derivatives as oxytocin agonists and vasopressin antagonists | FERRING B.V. (NL) | 2004-08-25 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050032777-A1 | Diazacycloalkanes as oxytocin agonists | OXTR, GNRHR, KISS1R | AVPR1A 8/4885OXTR 1/4885AVPR2 15/4885 |
| US-20080275026-A1 | Benzamide derivatives as oxytocin agonists and vasopressin antagonists | AVPR1A, AVPR2, AVPR1B | AVPR1A 1/4885OXTR 4/4885AVPR2 2/4885 |
| US-20060166971-A1 | Benzamide derivatives as oxytocin agonists and vasopressin antagonists | AVPR1A, AVPR2, AVPR1B | AVPR1A 1/4885OXTR 4/4885AVPR2 2/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.