SCHEMBL48326

SCHEMBL48326

Sc1c(Cl)c(Cl)cc(Cl)c1Cl

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 4/20 0.56
HPGD P15428 7/20 0.47
HSD17B10 Q99714 7/20 0.47
TSHR P16473 7/20 0.47
CASP1 P29466 1/20 0.47
ALDH1A1 P00352 3/20 0.44
MAPK1 P28482 3/20 0.43
CRHBP P24387 1/20 0.40
CRHR2 Q13324 1/20 0.40
AHR P35869 8/20 0.39
HSP90AA1 P07900 2/20 0.36
MEN1 O00255 1/20 0.36
NPC1 O15118 1/20 0.36
USP2 O75604 1/20 0.36
EGFR P00533 1/20 0.36
LMNA P02545 1/20 0.36
ESR1 P03372 1/20 0.36
ERBB2 P04626 1/20 0.36
CYP1A2 P05177 1/20 0.36
LCK P06239 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9357749 0.87 CYP3A4 (0.50) CYP3A4HPGDHSD17B10TSHRCASP1
SCHEMBL9387769 0.87 CYP3A4 (0.50) CYP3A4HPGDHSD17B10TSHRCASP1
SCHEMBL9480774 0.84 CYP3A4 (0.40) CYP3A4HPGDHSD17B10TSHRCASP1
SCHEMBL6520758 0.80 CYP3A4 (0.59) CYP3A4HPGDHSD17B10TSHRCASP1
SCHEMBL6512992 0.78 CYP3A4 (0.56) CYP3A4HPGDHSD17B10TSHRCASP1
SCHEMBL6512985 0.78 CYP3A4 (0.56) CYP3A4HPGDHSD17B10TSHRCASP1
SCHEMBL6511604 0.78 CYP3A4 (0.56) CYP3A4HPGDHSD17B10TSHRCASP1
Pentachlorobenzene SCHEMBL11455164 0.72 CYP3A4 (1.00) CYP3A4HPGDHSD17B10TSHRCASP1
Pentachlorobenzene SCHEMBL183144 0.72 CYP3A4 (1.00) CYP3A4HPGDHSD17B10TSHRCASP1
Pentachlorobenzene SCHEMBL11366199 0.71 CYP3A4 (0.79) CYP3A4HPGDHSD17B10TSHRCASP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 879 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7888432-B2 Having center, cover, or intermediate layer including reaction product that includes resilient polymer component, free radical source, zinc dimethacrylate and halogenated organosulfur compound; improved coefficient of restitution and increased compression ACUSHNET COMPANY (US) 2011-02-15 US claimed
US-7655732-B2 Low compression, resilient golf balls with rubber core ACUSHNET COMPANY (US) 2010-02-02 US claimed
US-20090011856-A1 LOW COMPRESSION, RESILIENT GOLF BALLS WITH RUBBER CORE JPMORGAN CHASE BANK, N.A., AS SUCCESSOR ADMINISTRATIVE AGENT 2009-01-08 US claimed
US-7446150-B2 Low compression, resilient golf balls with rubber core ACUSHNET COMPANY (US) 2008-11-04 US claimed
US-20080214739-A1 High cor golf ball using zinc dimethacrylate ACUSHNET COMPANY 2008-09-04 US claimed
US-7375153-B2 Zinc stearate-cis-to-trans catalyst blends for improved golf ball core compositions ACUSHNET COMPANY (US) 2008-05-20 US claimed
US-7342073-B2 High CoR golf ball using zinc dimethacrylate ACUSHNET COMPANY (US) 2008-03-11 US claimed
US-7157514-B2 Golf ball core compositions ACUSHNET COMPANY (US) 2007-01-02 US claimed
US-7071253-B2 Golf ball core compositions comprising unsaturated long chain organic acids and their salts ACUSHNET COMPANY (US) 2006-07-04 US claimed
US-7030192-B2 Golf ball cores comprising a halogenated organosulfur compound ACUSHNET COMPANY (US) 2006-04-18 US claimed
US-6762247-B2 ABRASION RESISTANCE; FEEL; REDUCED HARDNESS AND MODULUS; MODIFIED BUTADIENE POLYMER ACUSHNET COMPANY 2004-07-13 US claimed
US-20030207998-A1 Use of halogenated organosulfur and peroxide compounds in golf balls ACUSHNET COMPANY 2003-11-06 US claimed
US-6635716-B2 Golf ball core having decreased compression and/or increased coefficient of restitution ACUSHNET COMPANY 2003-10-21 US claimed
US-20030134955-A1 Polybutadiene rubber composition comprising a halogenated organosulfur compound or a metal salt thereof JPMORGAN CHASE BANK, N.A., AS SUCCESSOR ADMINISTRATIVE AGENT 2003-07-17 US claimed
US-20030130396-A1 Golf ball cores comprising a halogenated organosulfur compound ACUSHNET COMPANY 2003-07-10 US claimed
US-20030119989-A1 Low compression, resilient golf balls with rubber core ACUSHNET COMPANY 2003-06-26 US claimed
US-20030114249-A1 Golf ball core compositions comprising unsaturated long chain organic acids and their salts JPMORGAN CHASE BANK, N.A., AS SUCCESSOR ADMINISTRATIVE AGENT 2003-06-19 US claimed
US-20030064826-A1 Golf ball cores comprising a halogenated organosulfur compound JPMORGAN CHASE BANK, N.A., AS SUCCESSOR ADMINISTRATIVE AGENT 2003-04-03 US claimed
US-20020098915-A1 Thin, thermoset, polyurethane-covered golf ball with a dual core JPMORGAN CHASE BANK, N.A., AS SUCCESSOR ADMINISTRATIVE AGENT 2002-07-25 US claimed
US-5290911-A Forming polymers by catalytic oxidative coupling RESEARCH INSTITUTE FOR PRODUCTION DEVELOPMENT (JP) 1994-03-01 US claimed