SCHEMBL4833396

SCHEMBL4833396

O=C(Cc1cccc(O)c1)c1ccccc1

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CTBP2 P56545 1/20 0.56
MAPT P10636 2/20 0.53
L3MBTL1 Q9Y468 1/20 0.53
CA12 O43570 1/20 0.52
CA1 P00915 1/20 0.52
CA2 P00918 1/20 0.52
CA6 P23280 1/20 0.52
CA9 Q16790 1/20 0.52
SRD5A2 P31213 2/20 0.51
HIF1A Q16665 1/20 0.49
IDO1 P14902 1/20 0.47
OPRK1 P41145 1/20 0.47
ENPP2 Q13822 1/20 0.47
KDM4E B2RXH2 1/20 0.47
MEN1 O00255 1/20 0.47
CYP3A4 P08684 1/20 0.47
HPGD P15428 1/20 0.47
ALOX15 P16050 1/20 0.47
CES1 P23141 1/20 0.47
MAPK1 P28482 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6584846 0.91 CA12 (0.53) CTBP2CA12CA1CA2CA6
SCHEMBL30396060 0.89 CA12 (0.57) CTBP2MAPTL3MBTL1CA12CA1
SCHEMBL1515876 0.89 CA12 (0.57) CTBP2MAPTL3MBTL1CA12CA1
SCHEMBL2937591 0.89 NPC1 (0.56) CTBP2MAPTL3MBTL1SRD5A2ENPP2
SCHEMBL11633589 0.88 MAPT (0.60) MAPTL3MBTL1SRD5A2HIF1AKDM4E
Phenol SCHEMBL18694856 0.86 MAPT (0.63) MAPTL3MBTL1SRD5A2HIF1AKDM4E
SCHEMBL24403579 0.84 HTT (0.50) CTBP2MAPTL3MBTL1SRD5A2ENPP2
SCHEMBL13381372 0.83 SRD5A2 (0.62) MAPTL3MBTL1SRD5A2HIF1AKMT2A
SCHEMBL7475229 0.83 AKR1B1 (0.59) MAPTL3MBTL1SRD5A2KDM4EMEN1
SCHEMBL8008357 0.82 NPC1 (0.56) MAPTL3MBTL1CA12CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106547168-B Black matrix material composition and application 深圳市华星光电技术有限公司 2020-09-01 CN disclosed
CN-105093384-B Light guide plate and method for forming light guide plate 卡任特照明解决方案有限责任公司 2020-06-16 CN disclosed
US-10562875-B2 Aromatic compounds from furanics NEDERLANDSE ORGANISAITE VOOR TOEGEPAST-NATUURWETENSCHAPPELIJK ONDERZOEK TNO (NL) 2020-02-18 US disclosed
US-20190023678-A1 AROMATIC COMPOUNDS FROM FURANICS NEDERLANDSE ORGANISATIE VOOR TOEGEPAST-NATUURWETENSCHAPPELIJK ONDERZOEK TNO (NL) 2019-01-24 US disclosed
US-20080287466-A1 4-AMINO-2,3-DISUBSTITUTED THIENO [2,3,D]PYRIMIDINES AND PHARMACEUTICAL COMPOSITIONS THEREOF ADAMS JERRY LEROY 2008-11-20 US disclosed
US-7427623-B2 4-Amino-2,3-disubstituted thieno[2,3-d]pyrimidines and pharmacetical compositions thereof SMITHKLINE BEECHAM CORPORATION (US) 2008-09-23 US disclosed
US-20050004142-A1 Chemical compounds SMITHKLINE BEECHAM CORPORATION 2005-01-06 US disclosed
EP-1425284-A2 FURO- AND THIENOPYRIMIDINE DERIVATIVES AS ANGIOGENESIS INHIBITORS SMITHKLINE BEECHAM CORPORATION (US) 2004-06-09 EP disclosed
WO-2003022852-A2 FURO-AND THIENOPYRIMIDINE DERIVATIVES AS ANGIOGENESIS INHIBITORS SMITHKLINE BEECHAM CORPORATION (US) 2003-03-20 WO disclosed
EP-0627911-A4 PHOTOPOLYMERIZABLE BIODEGRADABLE HYDROGELS AS TISSUE CONTACTING MATERIALS AND CONTROLLED-RELEASE CARRIERS. UNIV TEXAS (US) 1995-07-26 EP disclosed
EP-0627911-A1 PHOTOPOLYMERIZABLE BIODEGRADABLE HYDROGELS AS TISSUE CONTACTING MATERIALS AND CONTROLLED-RELEASE CARRIERS THE BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) 1994-12-14 EP disclosed
WO-1993017669-A1 PHOTOPOLYMERIZABLE BIODEGRADABLE HYDROGELS AS TISSUE CONTACTING MATERIALS AND CONTROLLED-RELEASE CARRIERS BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) 1993-09-16 WO disclosed
EP-0481705-A1 Process for the preparation of arylalkylamines and substituted arylalkylamines HOECHST CELANESE CORPORATION (US) 1992-04-22 EP disclosed
US-5041669-A Reacting alkyl aryl ketones with alkyl nitrites, extracting product, catalytically hydrogenating/reducing in nonaqueous acid mixture HOECHST CELANESE CORPORATION (US) 1991-08-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190023678-A1 AROMATIC COMPOUNDS FROM FURANICS PAH, AOX1, TYR CTBP2 2794/4885MAPT 3857/4885L3MBTL1 4808/4885
US-20050004142-A1 Chemical compounds TIE1, KDR, TEK CTBP2 2257/4885MAPT 2499/4885L3MBTL1 3368/4885
US-10562875-B2 Aromatic compounds from furanics PAH, AOX1, TYR CTBP2 2794/4885MAPT 3857/4885L3MBTL1 4808/4885
US-20080287466-A1 4-AMINO-2,3-DISUBSTITUTED THIENO [2,3,D]PYRIMIDINES AND PHARMACEUTICAL COMPOSITIONS THEREOF TIE1, TEK, KDR CTBP2 2090/4885MAPT 2424/4885L3MBTL1 3908/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.