SCHEMBL4833849

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4831025	0.82	CCNC (0.46)	PRMT5WDR77TGFBR1ALDH1A1KDM4E
	SCHEMBL4831013	0.82	CCNC (0.46)	PRMT5WDR77TGFBR1ALDH1A1KDM4E
	SCHEMBL4829235	0.82	PRMT5 (0.44)	PRMT5WDR77TGFBR1ALDH1A1KDM4C
	SCHEMBL3630473	0.81	NR3C2 (0.41)	PRMT5WDR77ALDH1A1KDM4EHIF1A
	SCHEMBL4836837	0.81	LMNA (0.46)	PRMT5WDR77ALDH1A1KDM4EHIF1A
	SCHEMBL23087238	0.77	HTR2A (0.50)	PRMT5WDR77TGFBR1IDO1HTR2A
	SCHEMBL15428631	0.77	PRMT5 (0.46)	PRMT5WDR77TGFBR1KDM4EIDO1
	SCHEMBL29735245	0.77	HTR2A (0.50)	PRMT5WDR77TGFBR1IDO1HTR2A
	SCHEMBL4833921	0.76	ERN1 (0.47)	ALDH1A1CYP1A2CYP3A4HIF1AERN1
	SCHEMBL12776206	0.74	PRMT5 (0.43)	PRMT5WDR77TGFBR1KDM4CGRIN2B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.