⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL4834350 | 0.93 | SCD (0.36) | — | |
| SCHEMBL4843804 | 0.84 | HDAC3 (0.35) | — | |
| SCHEMBL6247249 | 0.83 | KDM4E (0.40) | — | |
| SCHEMBL4841793 | 0.80 | MAPT (0.41) | — | |
| SCHEMBL4843854 | 0.79 | KMT2A (0.48) | — | |
| Trifluoroacetic Acid SCHEMBL4839359 | 0.79 | SCD (0.38) | — | |
| SCHEMBL4845549 | 0.79 | NPC1 (0.40) | — | |
| SCHEMBL5263244 | 0.79 | ALDH1A1 (0.49) | — | |
| SCHEMBL4834900 | 0.79 | MAPT (0.45) | — | |
| SCHEMBL4838763 | 0.78 | MEN1 (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1539759-B1 | NOVEL IMIDAZOPYRIDINES AND THEIR USE | ASTRAZENECA AB (SE) | 2007-08-15 | — | — | EP | claimed |
| US-20050261333-A1 | Use of and some novel imidazopyridines | ASTRAZENECA A B (SE) | 2005-11-24 | — | — | US | claimed |
| US-7410966-B2 | Use of and some novel imidazopyridines | ASTRAZENECA AB (SE) | 2008-08-12 | — | — | US | disclosed |
| EP-1539759-B1 | NOVEL IMIDAZOPYRIDINES AND THEIR USE | ASTRAZENECA AB (SE) | 2007-08-15 | — | — | EP | disclosed |
| US-20050261333-A1 | Use of and some novel imidazopyridines | ASTRAZENECA A B (SE) | 2005-11-24 | — | — | US | disclosed |