Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4843616 | 0.86 | — | — | |
| SCHEMBL4841793 | 0.81 | MAPT (0.41) | MAPT | |
| Trifluoroacetic Acid SCHEMBL4844154 | 0.80 | ADRB1 (0.39) | MEN1KMT2A | |
| SCHEMBL4838763 | 0.80 | MEN1 (0.42) | MEN1KMT2A | |
| SCHEMBL4841671 | 0.80 | CYP3A4 (0.43) | — | |
| SCHEMBL4842323 | 0.79 | ALDH1A1 (0.45) | ALDH1A1KMT2A | |
| SCHEMBL4834900 | 0.79 | MAPT (0.45) | MAPT | |
| SCHEMBL4833883 | 0.79 | — | — | |
| SCHEMBL4843854 | 0.78 | KMT2A (0.48) | ALDH1A1MAPTLMNAMEN1HTT | |
| SCHEMBL4842028 | 0.78 | MAPK1 (0.46) | MAPTKDM4ELMNAMEN1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1539759-B1 | NOVEL IMIDAZOPYRIDINES AND THEIR USE | ASTRAZENECA AB (SE) | 2007-08-15 | — | — | EP | claimed |