SCHEMBL483392

SCHEMBL483392

c1ccc2c(c1)CC1C2C2Cc3ccccc3C12

nearest known ligand 0.65

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
KDM1A O60341 10/20 0.65
KDM1B Q8NB78 3/20 0.49
CYP11B2 P19099 1/20 0.45
GRIN2D O15399 1/20 0.45
GRIN3B O60391 1/20 0.45
GRIN1 Q05586 1/20 0.45
GRIN2A Q12879 1/20 0.45
GRIN2B Q13224 1/20 0.45
GRIN2C Q14957 1/20 0.45
GRIN3A Q8TCU5 1/20 0.45
CHRNB2 P17787 1/20 0.43
CHRNA4 P43681 1/20 0.43
HTR2A P28223 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28611238 0.81 KDM1A (0.96) KDM1AKDM1BCYP11B2HTR2A
SCHEMBL24278848 0.80 KDM1A (0.50) KDM1AKDM1BCYP11B2GRIN2DGRIN3B
SCHEMBL24278721 0.80 KDM1A (0.50) KDM1AKDM1BCYP11B2GRIN2DGRIN3B
SCHEMBL413013 0.77 KDM1A (0.52) KDM1AKDM1BCYP11B2GRIN2DGRIN3B
SCHEMBL29370901 0.77 KDM1A (0.52) KDM1AKDM1BCYP11B2GRIN2DGRIN3B
SCHEMBL28386740 0.77 KDM1A (0.52) KDM1AKDM1BCYP11B2HTR2A
SCHEMBL22210207 0.77 KDM1A (0.52) KDM1AKDM1BCYP11B2GRIN2DGRIN3B
SCHEMBL7972799 0.77 KDM1A (0.52) KDM1AKDM1BCYP11B2GRIN2DGRIN3B
SCHEMBL29785782 0.75 KDM1A (0.46) KDM1AKDM1BCYP11B2GRIN2DGRIN3B
SCHEMBL1478222 0.75 KDM1A (0.50) KDM1AKDM1BCYP11B2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 49 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8524116-B2 Multilayer sheet containing optically anisotropic layer containing liquid crystal compound and cellulose ester with polymer FUJIFILM CORPORATION (JP) 2013-09-03 US disclosed
US-20120229734-A1 OPTICAL FILM, OPTICAL COMPENSATION FILM, POLARIZING PLATE AND LIQUID-CRYSTAL DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2012-09-13 US disclosed
US-8184245-B2 Optical compensation film for VA-mode liquid crystal display device and VA-mode liquid crystal display device FUJIFILM CORPORATION (JP) 2012-05-22 US disclosed
US-8164722-B2 Liquid-crystal display device with at least three optically-anisotropic layers having formulated in-plane retardations FUJIFILM CORPORATION (JP) 2012-04-24 US disclosed
EP-1794216-B1 CELLULOSE ACYLATE FILM, OPTICAL COMPENSATION FILM, POLARIZING PLATE, AND LIQUID CRYSTAL DISPLAY DEVICE FUJIFILM CORP (JP) 2012-02-01 EP disclosed
CN-101784946-B Liquid-crystal display device FUJIFILM CORP. (JP) 2011-12-07 CN disclosed
US-8064009-B2 Liquid crystal cell and liquid crystal display apparatus FUJIFILM CORPORATION (JP) 2011-11-22 US disclosed
CN-1685252-B Process for preparing retarders FUJI PHOTO FILM CO LTD 2011-09-28 CN disclosed
US-7929089-B2 Optical compensation film, polarizing plate, and liquid-crystal display device FUJIFILM CORPORATION (JP) 2011-04-19 US disclosed
US-7804565-B2 Cellulose acylate film, optical compensation film, polarizing plate, and liquid crystal display device FUJIFILM CORPORATION (JP) 2010-09-28 US disclosed
US-20060051523-A1 Sptical compensatory sheet and method for preparing optically anisotropic layer FUJI PHOTO FILM CO., LTD. (JP) 2006-03-09 US disclosed
WO-2006016723-A1 CELLULOSE ACYLATE FILM, OPTICAL COMPENSATION FILM, POLARIZING PLATE, AND LIQUID CRYSTAL DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2006-02-16 WO disclosed
US-20060035037-A1 Composition, optical film, polarizing plate and liquid crystal display FUJI PHOTO FILM CO., LTD. (JP) 2006-02-16 US disclosed
WO-2006001504-A1 OPTICAL COMPENSATORY FILM, PROCESS FOR PRODUCING THE SAME, AND POLARIZING PLATE AND LIQUID CRYSTAL DISPLAY EMPLOYING THE SAME FUJI PHOTO FILM CO., LTD. (JP) 2006-01-05 WO disclosed
CN-1685252-A Processe for preparing retarders FUJI PHOTO FILM CO LTD (JP) 2005-10-19 CN disclosed
CN-1653381-A Optical compensatory sheet and method for preparing optically anisotropic layer FUJI PHOTO FILM CO LTD (JP) 2005-08-10 CN disclosed
US-20050157225-A1 Liquid-crystal display and polarizing plate FUJI PHOTO FILM CO., LTD. (JP) 2005-07-21 US disclosed
US-20040234706-A1 Optical compensatory sheet, elliptical polarizing plates and liquid-crystal display FUJI PHOTO FILM CO., LTD. (JP) 2004-11-25 US disclosed
WO-2004029695-A2 PROCESSE FOR PREPARING RETARDERS FUJI PHOTO FILM CO., LTD. (JP) 2004-04-08 WO disclosed
WO-2003098337-A2 SPTICAL COMPENSATORY SHEET AND METHOD FOR PREPARING OPTICALLY ANISOTROPIC LAYER FUJI PHOTO FILM CO., LTD. (JP) 2003-11-27 WO disclosed