SCHEMBL413013

SCHEMBL413013

C1=CC2CC1C1Cc3ccccc3C21

nearest known ligand 0.52

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
KDM1A O60341 10/20 0.52
KDM1B Q8NB78 3/20 0.41
CYP11B2 P19099 1/20 0.37
GRIN2D O15399 1/20 0.36
GRIN3B O60391 1/20 0.36
GRIN1 Q05586 1/20 0.36
GRIN2A Q12879 1/20 0.36
GRIN2B Q13224 1/20 0.36
GRIN2C Q14957 1/20 0.36
GRIN3A Q8TCU5 1/20 0.36
CHRNB2 P17787 2/20 0.36
CHRNA4 P43681 2/20 0.36
SIGMAR1 Q99720 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29370901 1.00 KDM1A (0.52) KDM1AKDM1BCYP11B2GRIN2DGRIN3B
SCHEMBL5993533 0.81 CYP11B2 (0.54) KDM1ACYP11B2
SCHEMBL852834 0.79 IDO1 (0.39) KDM1A
SCHEMBL29442080 0.79 IDO1 (0.39) KDM1A
SCHEMBL29785782 0.79 KDM1A (0.46) KDM1AKDM1BCYP11B2GRIN2DGRIN3B
SCHEMBL483392 0.77 KDM1A (0.65) KDM1AKDM1BCYP11B2GRIN2DGRIN3B
SCHEMBL8421976 0.75 KDM1A (0.41) KDM1A
SCHEMBL30177612 0.73 KDM1A (0.40) KDM1AGRIN2DGRIN3BGRIN1GRIN2A
SCHEMBL4402522 0.72 CHRNB2 (0.46) CHRNB2CHRNA4
SCHEMBL10068329 0.72 KDM1A (0.33) KDM1AKDM1B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1067 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4288479-A1 LONG SHELF LIFE STABLE PHOTOACTIVE MASS POLYMERIZABLE POLYCYCLOOLEFIN COMPOSITIONS AS OPTICAL MATERIALS Promerus, LLC (US) 2023-12-13 EP claimed
WO-2022169801-A1 LONG SHELF LIFE STABLE PHOTOACTIVE MASS POLYMERIZABLE POLYCYCLOOLEFIN COMPOSITIONS AS OPTICAL MATERIALS PROMERUS, LLC (US) 2022-08-11 WO claimed
US-20100074083-A1 RESIN COMPOSITION AND MOLDED PRODUCT OBTAINED BY MOLDING THE RESIN COMPOSITION MITSUI CHEMICALS, INC. (JP) 2010-03-25 US claimed
US-20050243245-A1 Polarizing plate and production process of the same FUJI PHOTO FILM CO., LTD. (JP) 2005-11-03 US claimed
EP-1006134-B1 NORBORNENE POLYMER AND PROCESS FOR THE PREPARATION THEREOF NIPPON ZEON CO (JP) 2003-10-15 EP claimed
EP-0888265-B1 METHOD FOR PREPARING NORBORNENE AND SUBSTITUTED DERIVATIVES OF NORBORNENE OPTATECH CORP (FI) 2003-07-30 EP claimed
US-6525144-B1 Heat resistant, nondeforming molding materials NIPPON ZEON CO., LTD. (JP) 2003-02-25 US claimed
EP-0447072-B1 Cycloolefin random copolymer and process for preparing same MITSUI CHEMICALS INC (JP) 2002-01-16 EP claimed
EP-0784066-B1 HYDROGENATED RING-OPENING POLYMER NIPPON ZEON CO (JP) 2002-01-16 EP claimed
EP-1020420-A1 1,4-METHANO-1,4,4a,9a-TETRAHYDROFLUORENE COMPOSITION AND PROCESS FOR PRODUCING THE SAME Nippon Petrochemicals Company, Limited (JP) 2000-07-19 EP claimed
EP-0824554-B1 AMORPHOUS OLEFIN CO/TER-POLYMERS OPTATECH CORP (FI) 2000-03-01 EP claimed
US-5905129-A Ring-opening polymer hydrogenation products NIPPON ZEON CO., LTD. (JP) 1999-05-18 US claimed
EP-0888265-A1 METHOD FOR PREPARING NORBORNENE AND SUBSTITUTED DERIVATIVES OF NORBORNENE OPTATECH CORPORATION (FI) 1999-01-07 EP claimed
WO-1997033848-A1 METHOD FOR PREPARING NORBORNENE AND SUBSTITUTED DERIVATIVES OF NORBORNENE OPTATECH CORPORATION (FI) 1997-09-18 WO claimed
EP-0784066-A1 HYDROGENATED RING-OPENING POLYMER NIPPON ZEON CO., LTD. (JP) 1997-07-16 EP claimed
EP-0446051-B1 Process for the production of cycloolefin-based random copolymer MITSUI PETROCHEMICAL IND (JP) 1995-11-15 EP claimed
EP-0325260-B1 Random copolymer containing derivative of bicyclo (2.2.1) hept-2-ene compound NIPPON OIL CO LTD (JP) 1994-11-02 EP claimed
EP-0542488-B1 Process for preparing cycloolefin random copolymer MITSUI PETROCHEMICAL IND (JP) 1994-07-06 EP claimed
US-5225503-A Catalyst MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1993-07-06 US claimed
EP-0542488-A1 Process for preparing cycloolefin random copolymer MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1993-05-19 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100074083-A1 RESIN COMPOSITION AND MOLDED PRODUCT OBTAINED BY MOLDING THE RESIN COMPOSITION SEM1, WDR5, WDR1 KDM1A 271/4885KDM1B 510/4885CYP11B2 4884/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.