SCHEMBL483397

SCHEMBL483397

Nc1ccc(-c2ccc(N)cc2O)c(O)c1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CASP1 P29466 3/20 0.59
TSHR P16473 3/20 0.59
CA1 P00915 2/20 0.52
CA2 P00918 2/20 0.52
PDE10A Q9Y233 1/20 0.52
ALDH1A1 P00352 5/20 0.52
CYP3A4 P08684 4/20 0.52
KDM4E B2RXH2 3/20 0.52
MAPT P10636 3/20 0.52
GAA P10253 3/20 0.52
ESR2 Q92731 1/20 0.52
PTPN1 P18031 1/20 0.52
TDP1 Q9NUW8 4/20 0.48
ALOX15 P16050 3/20 0.48
HSD17B10 Q99714 3/20 0.48
POLB P06746 2/20 0.48
MAPK1 P28482 2/20 0.48
L3MBTL1 Q9Y468 1/20 0.48
THRB P10828 2/20 0.46
HIF1A Q16665 2/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29484239 1.00 CASP1 (0.59) CASP1TSHRCA1CA2PDE10A
Methane SCHEMBL28033104 0.97 CASP1 (0.56) CASP1TSHRCA1CA2PDE10A
SCHEMBL28033075 0.92 CASP1 (0.52) CASP1TSHRCA1CA2PDE10A
SCHEMBL5685322 0.89 CASP1 (0.50) CASP1TSHRCA1CA2PDE10A
SCHEMBL6783805 0.89 PDE10A (0.56) CASP1TSHRCA1CA2PDE10A
SCHEMBL5687674 0.89 ALDH1A1 (0.50) CASP1TSHRCA1CA2PDE10A
SCHEMBL28053536 0.89 ALDH1A1 (0.56) CASP1TSHRCA1CA2PDE10A
SCHEMBL5688007 0.87 TSHR (0.48) CASP1TSHRCA1CA2PDE10A
SCHEMBL5687750 0.87 SMN1; SMN2 (0.50) CASP1TSHRCA1CA2PDE10A
SCHEMBL8781157 0.85 TSHR (0.46) CASP1TSHRCA1CA2PDE10A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 540 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-120020124-A Low-tension foaming agent and preparation method and application thereof 中国石油化工股份有限公司 2025-05-20 CN claimed
CN-115746231-B High-temperature-resistant easy-to-process benzoxazole resin and preparation method and application thereof 中国科学院宁波材料技术与工程研究所 2025-05-02 CN claimed
CN-119570027-B Colored end-capped photosensitive polymer, preparation method and application thereof, black photoresist and black matrix 上海明士华新材料有限公司 2025-04-18 CN claimed
CN-119570027-A Colored end-capped photosensitive polymer, preparation method and application thereof, black photoresist and black matrix 上海明士华新材料有限公司 2025-03-07 CN claimed
CN-119431779-A Photosensitive composition 德山新勒克斯有限公司 2025-02-14 CN claimed
CN-119039543-A Preparation method and application of efficient cadmium-removing ionic covalent organic framework material 哈尔滨工业大学 2024-11-29 CN claimed
CN-118359938-B Heat-resistant anti-aging SBS modified asphalt and preparation process thereof 陕西交控公路沥青材料技术有限责任公司 2024-11-15 CN claimed
CN-118125972-B Diamine monomer with nitrogen heterocycle and benzocyclobutene structure, and preparation method and application thereof 波米科技有限公司 2024-09-20 CN claimed
CN-118359938-A Heat-resistant anti-aging SBS modified asphalt and preparation process thereof 陕西交控公路沥青材料技术有限责任公司 2024-07-19 CN claimed
CN-118206916-A Composite antifouling coating and preparation method and application thereof 中山大学 2024-06-18 CN claimed
EP-2555053-A1 Positive-type photosensitive resin composition Toray Industries, Inc. (JP) 2013-02-06 EP claimed
US-7648815-B2 Solvent solubility; adhesive; heat resistance; dielectric film pattern PI R&D CO., LTD. (JP) 2010-01-19 US claimed
EP-1395627-A1 POLYIMIDE COMPOSITION HAVING IMPROVED PEEL STRENGTH E.I. DU PONT DE NEMOURS AND COMPANY (US) 2004-03-10 EP claimed
WO-2002090422-A1 POLYIMIDE COMPOSITION HAVING IMPROVED PEEL STRENGTH E.I. DU PONT DE NEMOURS AND COMPANY (US) 2002-11-14 WO claimed
US-6383258-B1 FROM O-TOLIDINE SULFONE AND DIAMINE L'AIR LIQUIDE SOCIETE ANONYME POUR L'ETUDE ET L'EXPLOITATION DES PROCEDES GEORGES CLAUDE (FR) 2002-05-07 US claimed
US-5126410-A Solvent resistant polybenzoxazoles, polybenzothiazoles and polybenzimidazoles THE BOEING COMPANY (US) 1992-06-30 US claimed
US-5120819-A Heat and sovent-resistant polybenzoxazoles,-thiazoles and -imidazoles for aerospace applications BOEING COMPANY (US) 1992-06-09 US claimed
US-4965336-A PHENYLIMIDE ACID HALIDE ENCAPPED POLYBENZOXAZLES; CURABLE, SOLVENT RESISTANCE PREPREGS THE BOEING COMPANY (US) 1990-10-23 US claimed
EP-0309649-A2 High performance heterocycle oligomers and blends THE BOEING COMPANY (US) 1989-04-05 EP claimed
EP-0291778-A1 Process for the preparation of high temperature-resistant dielectrics SIEMENS AKTIENGESELLSCHAFT (DE) 1988-11-23 EP claimed