SCHEMBL4834394

SCHEMBL4834394

COc1cccc(N2CCOCC2)c1

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ADRB1 P08588 1/20 0.65
MAPT P10636 3/20 0.59
NPC1 O15118 1/20 0.59
DRD2 P14416 1/20 0.58
KCNH2 Q12809 1/20 0.58
GAA P10253 1/20 0.55
ALOX15 P16050 1/20 0.55
ALOX12 P18054 1/20 0.55
HSD17B10 Q99714 1/20 0.55
L3MBTL1 Q9Y468 1/20 0.55
LMNA P02545 1/20 0.55
FAAH O00519 1/20 0.54
AGXT P21549 1/20 0.54
MEN1 O00255 1/20 0.54
CYP1A2 P05177 1/20 0.54
CYP3A4 P08684 1/20 0.54
CYP2C9 P11712 1/20 0.54
CYP2C19 P33261 1/20 0.54
KMT2A Q03164 1/20 0.54
PRKDC P78527 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Nitrogen SCHEMBL8429553 0.97 ADRB1 (0.61) ADRB1MAPTNPC1DRD2KCNH2
Nitrogen SCHEMBL1855134 0.95 ADRB1 (0.59) ADRB1MAPTNPC1DRD2KCNH2
SCHEMBL11074672 0.87 ADRB1 (0.76) ADRB1MAPTNPC1DRD2KCNH2
SCHEMBL19212406 0.85 ADRB1 (0.69) ADRB1MAPTNPC1DRD2KCNH2
SCHEMBL29194717 0.85 MAPT (0.64) ADRB1MAPTDRD2KCNH2GAA
SCHEMBL30246093 0.85 MAPT (0.64) ADRB1MAPTDRD2KCNH2GAA
SCHEMBL23675047 0.83 ADRB1 (0.71) ADRB1MAPTNPC1DRD2KCNH2
SCHEMBL5448570 0.83 ADRB1 (0.61) ADRB1MAPTALOX15HSD17B10L3MBTL1
SCHEMBL3051915 0.83 ADRB1 (0.71) ADRB1MAPTNPC1DRD2KCNH2
SCHEMBL30255158 0.83 ADRB1 (0.71) ADRB1MAPTNPC1DRD2KCNH2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 110 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113135835-A Method for exciting C-C bond breaking acylation and application 广州中医药大学(广州中医药研究院) 2021-07-20 CN claimed
EP-1351946-A2 MATERIALS AND METHODS TO POTENTIATE CANCER TREATMENT ICOS CORPORATION (US) 2003-10-15 EP claimed
US-20020165218-A1 Materials and methods to potentiate cancer treatment LUITPOLD PHARMACEUTICALS, INC. 2002-11-07 US claimed
WO-2002020500-A2 MATERIALS AND METHODS TO POTENTIATE CANCER TREATMENT ICOS CORPORATION (US) 2002-03-14 WO claimed
EP-0673784-B1 Recording sheets containing oxazole, isooxazole, oxazolidinone, oxazoline salts, morpholine, thiazole, thiazolidine, thiadiazole, and phenothiazine compounds XEROX CORP (US) 1999-10-27 EP claimed
US-12392042-B2 Alternating current (AC) transition-metal catalysis YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) 2025-08-19 US disclosed
US-20230407492-A1 ALTERNATING CURRENT (AC) TRANSITION-METAL CATALYSIS YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) 2023-12-21 US disclosed
EP-4214355-A1 ALTERNATING CURRENT (AC) TRANSITION-METAL CATALYSIS Yeda Research and Development Co. Ltd (IL) 2023-07-26 EP disclosed
CN-116113728-A Alternating Current (AC) transition metal catalysis 耶达研究与发展有限公司 2023-05-12 CN disclosed
WO-2022203429-A1 COMPOSITION FOR PREVENTING OR TREATING MULTIPLE SCLEROSIS CHONG KUN DANG PHARMACEUTICAL CORP. (KR) 2022-09-29 WO disclosed
CN-111217816-B FLT3 kinase inhibitor and preparation and application thereof 中国科学院上海药物研究所 2022-08-16 CN disclosed
CN-111116653-B Preparation method of pyrazole-triazole phosphine compound 河北工业大学 2022-08-12 CN disclosed
WO-2002020500-A2 MATERIALS AND METHODS TO POTENTIATE CANCER TREATMENT ICOS CORPORATION (US) 2002-03-14 WO disclosed
EP-0802173-B1 Process for producing heterocylic aromatic amine or arylamine TOSOH CORP (JP) 2001-12-19 EP disclosed
US-6235938-B1 ARYLATION IN THE PRESENCE OF A BASE AND TRANSITION METAL CATALYSTS TO FORM N-ARYLAMINE AND GROUP 8 METAL YALE UNIVERSITY 2001-05-22 US disclosed
EP-1025095-A1 SUBSTITUTED CHROMAN DERIVATIVES AstraZeneca AB (SE) 2000-08-09 EP disclosed
US-5929281-A REACTING A HETROCYCLIC AROMATIC HALIDE WITH AN AMINE COMPOUND IN PRESENCE OF A BASE USING A TRI-TERT-BUTYLPHOSPHINE AND PALLADIUM COMPOUND CATALYST TO FORM HETEROCYCLIC AROMATIC AMINE COMPOUNDS TOSOH CORPORATION (JP) 1999-07-27 US disclosed
WO-1999014212-A1 SUBSTITUTED CHROMAN DERIVATIVES ASTRAZENECA AB (SE) 1999-03-25 WO disclosed
EP-0802173-A1 Process for producing heterocylic aromatic amine or arylamine Tosoh Corporation (JP) 1997-10-22 EP disclosed
US-4200751-A COLOR-FORMING AGENTS YAMAMOTO KAGAKU GOSEI CO., LTD. (JP) 1980-04-29 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020165218-A1 Materials and methods to potentiate cancer treatment DCK, CHEK2, CHEK1 ADRB1 4505/4885MAPT 4502/4885NPC1 1993/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.