SCHEMBL483453

SCHEMBL483453

C=CC(=O)NCOP(=O)(OCNC(=O)C=C)OP(=O)(O)O

nearest known ligand 0.42

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 2/20 0.42
ALDH1A1 P00352 1/20 0.42
TSHR P16473 1/20 0.42
MAPK1 P28482 1/20 0.42
ZDHHC20 Q5W0Z9 1/20 0.33
ZDHHC2 Q9UIJ5 1/20 0.33
FDPS P14324 1/20 0.31
BLM P54132 1/20 0.31
TGM2 P21980 1/20 0.31
BTN3A1 O00481 1/20 0.30
LPAR2 Q9HBW0 1/20 0.30
LPAR3 Q9UBY5 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14678814 0.85 TSHR (0.48) TDP1ALDH1A1TSHRMAPK1ZDHHC20
SCHEMBL483452 0.81 ALDH1A1 (0.45) TDP1ALDH1A1TSHRMAPK1ZDHHC20
SCHEMBL483610 0.81 TSHR (0.48) TDP1ALDH1A1TSHRMAPK1ZDHHC20
SCHEMBL337894 0.72 TSHR (0.44) TDP1ALDH1A1TSHRMAPK1ZDHHC20
SCHEMBL16372096 0.71 LPAR3 (0.49) TDP1ALDH1A1TSHRMAPK1ZDHHC20
SCHEMBL21091698 0.71 TDP1 (0.47) TDP1ALDH1A1TSHRMAPK1ZDHHC20
SCHEMBL907318 0.70 ALDH1A1 (0.45) TDP1ALDH1A1TSHRMAPK1ZDHHC20
SCHEMBL844941 0.69 TSHR (0.59) TDP1ALDH1A1TSHRMAPK1ZDHHC20
SCHEMBL2867142 0.69 BTN3A1 (0.39) TDP1FDPSBLMBTN3A1LPAR2
SCHEMBL25503763 0.68 ALDH1A1 (0.46) TDP1ALDH1A1TSHRMAPK1ZDHHC20

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2412677-A1 ORGANIC-INORGANIC COMPOSITE MATERIAL AND PROCESS FOR PRODUCING SAME National University Corporation Okayama University (JP) 2012-02-01 EP disclosed