SCHEMBL844941

SCHEMBL844941

C=CC(=O)NCOCNC(=O)C=C

nearest known ligand 0.59

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
TSHR P16473 8/20 0.59
ALDH1A1 P00352 7/20 0.59
MAPK1 P28482 1/20 0.59
TDP1 Q9NUW8 1/20 0.59
ZDHHC20 Q5W0Z9 1/20 0.43
ZDHHC2 Q9UIJ5 1/20 0.43
TGM2 P21980 7/20 0.39
TP53 P04637 2/20 0.36
HIF1A Q16665 2/20 0.36
HSD17B10 Q99714 1/20 0.36
LMNA P02545 2/20 0.32
CYP3A4 P08684 1/20 0.31
GAA P10253 1/20 0.31
FGFR4 P22455 1/20 0.30
F13A1 P00488 1/20 0.30
TGM1 P22735 1/20 0.30
TGM3 Q08188 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10626929 0.92 TSHR (0.56) TSHRALDH1A1MAPK1TDP1ZDHHC20
SCHEMBL9786661 0.90 TSHR (0.54) TSHRALDH1A1MAPK1TDP1ZDHHC20
Ether SCHEMBL8375535 0.89 TSHR (0.48) TSHRALDH1A1MAPK1TDP1ZDHHC20
Ethylene Glycol SCHEMBL5904195 0.87 TSHR (0.46) TSHRALDH1A1MAPK1TDP1ZDHHC20
SCHEMBL251019 0.86 TSHR (0.50) TSHRALDH1A1MAPK1TDP1ZDHHC20
SCHEMBL28214296 0.86 TSHR (0.50) TSHRALDH1A1MAPK1TDP1ZDHHC20
SCHEMBL34047 0.86
SCHEMBL11795609 0.84 TSHR (0.48) TSHRALDH1A1MAPK1TDP1ZDHHC20
SCHEMBL16749550 0.84 ALDH1A1 (0.48) TSHRALDH1A1MAPK1TDP1ZDHHC20
SCHEMBL7157903 0.84 TSHR (0.48) TSHRALDH1A1MAPK1TDP1ZDHHC20

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 491 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109312011-B Method for producing DN gel film 住友化学株式会社 2020-11-24 CN claimed
US-20200316529-A1 METHOD FOR PRODUCING DN GEL MEMBRANE SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2020-10-08 US claimed
EP-3466987-A1 METHOD FOR PRODUCING DN GEL MEMBRANE Sumitomo Chemical Company Limited (JP) 2019-04-10 EP claimed
US-6418889-B1 MOLDING WATER JACKET CORE; WASTE SAND DISCHARGING RYOBI LTD. (JP) 2002-07-16 US claimed
EP-1170496-A1 Closed deck type cylinder block and method for producing the same RYOBI LTD. (JP) 2002-01-09 EP claimed
US-4634727-A VINYL ACETATE POLYMER AND LECITHIN FOR BONDING WOOD NATIONAL STARCH AND CHEMICAL CORPORATION (US) 1987-01-06 US claimed
US-4486532-A IMMOBILIZATION OF FUMARASE-PRODUCING MICROORGANISM TNANBE SEIYAKU CO., LTD. (JP) 1984-12-04 US claimed
US-4275156-A ACRYLAMIDOMETHYLATED MONOVINYL AROMATIC POLYMER SUBSTRATE TORAY INDUSTRIES, INC. (JP) 1981-06-23 US claimed
EP-0015367-A2 Immobilized glucose isomerase, process for preparing it and process for preparing fructose from glucose TORAY INDUSTRIES, INC. (JP) 1980-09-17 EP claimed
US-4116855-A N,N'-((THIOCARBONYL)THIO)DIMORPHOLINE, AMIDES, ESTERS AMERICAN CYANAMID COMPANY (US) 1978-09-26 US claimed
US-4081327-A IMMOBILIZED GLUCOSE ISOMERASE-PRODUCING MICROORGANISM TANABE SEIYAKU CO., LTD. (JA) 1978-03-28 US claimed
US-3953291-A IMMOBILIZED ENZYMES TANABE SEIYAKU CO., LTD. (JA) 1976-04-27 US claimed
US-12528158-B2 Abrasive article and method of making the same 3M INNOVATIVE PROPERTIES COMPANY (US) 2026-01-20 US disclosed
EP-4658145-A1 ABRASIVE ARTICLE 3M Innovative Properties Company (US) 2025-12-10 EP disclosed
US-12459081-B2 Treated backing and coated abrasive article including the same 3M INNOVATIVE PROPERTIES COMPANY (US) 2025-11-04 US disclosed
EP-3727749-B1 ABRASIVE ARTICLES INCLUDING A SATURANT AND AN ANTI-LOADING SIZE LAYER 3M INNOVATIVE PROPERTIES COMPANY (US) 2025-08-06 EP disclosed
US-3898127-A Process for preparing urocanic acid TANABE SEIYAKU CO 1975-08-05 US disclosed
US-3898128-A Process for preparing L-alanine TANABE SEIYAKU CO 1975-08-05 US disclosed
US-3886040-A Novel Process for preparing L-citrulline TANABE SEIYAKU CO 1975-05-27 US disclosed
US-3791926-A PROCESS FOR THE PRODUCTION OF L-ASPARTIC ACID TANABE SEIYAKU CO 1974-02-12 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12528158-B2 Abrasive article and method of making the same ITGAV, ILK, ITGA2 TSHR 4182/4885ALDH1A1 2658/4885MAPK1 4134/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.