SCHEMBL4834591

SCHEMBL4834591

C=C(C(=O)O)[Si](CCCCCCCCCCCC)(CCCCCCCCCCCC)CCCCCCCCCCCC

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GPR84 Q9NQS5 7/20 0.41
PPARG P37231 7/20 0.41
PPARD Q03181 7/20 0.41
PPARA Q07869 7/20 0.41
HDAC11 Q96DB2 5/20 0.41
TSHR P16473 4/20 0.41
PTPN1 P18031 3/20 0.41
ALDH1A1 P00352 2/20 0.41
TLR2 O60603 2/20 0.41
TDP1 Q9NUW8 2/20 0.41
FABP4 P15090 2/20 0.41
SLC22A6 Q4U2R8 1/20 0.41
SLC22A8 Q8TCC7 1/20 0.41
MEN1 O00255 1/20 0.41
ESR1 P03372 1/20 0.41
ALOX15 P16050 1/20 0.41
PDE4A P27815 1/20 0.41
KMT2A Q03164 1/20 0.41
PDE3A Q14432 1/20 0.41
HSD17B10 Q99714 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4830323 1.00 GPR84 (0.41) GPR84PPARGPPARDPPARAHDAC11
SCHEMBL5164656 0.98 AKR1B1 (0.39) GPR84PPARGPPARDPPARAHDAC11
SCHEMBL4832778 0.91 AKR1B1 (0.36) GPR84PPARGPPARDPPARAHDAC11
SCHEMBL4832840 0.82 FFAR3 (0.32)
Dodecane SCHEMBL17222843 0.72 TSHR (0.56) GPR84PPARGPPARDPPARAHDAC11
Dodecane SCHEMBL821201 0.72 TSHR (0.56) GPR84PPARGPPARDPPARAHDAC11
Decane SCHEMBL2509675 0.72 TSHR (0.56) GPR84PPARGPPARDPPARAHDAC11
Decane SCHEMBL20943079 0.72 TSHR (0.56) GPR84PPARGPPARDPPARAHDAC11
Octane SCHEMBL2702853 0.72 TSHR (0.56) GPR84PPARGPPARDPPARAHDAC11
Methacrylic Acid SCHEMBL8469735 0.72 TSHR (0.56) GPR84PPARGPPARDPPARAHDAC11

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1954753-B1 PAINT CONTAINING METAL SALT OF PYRITHIONE AND CUPROUX OXIDE ARCH CHEM INC (US) 2012-11-21 EP disclosed
US-7435771-B2 Stabilized against viscosity change, gelation and agglomeration during formulation and storage; storage stability, gel-free; hydrolysable acrylate resin selected from copper acrylate, zinc acrylate, silyl acrylate; benzoic acid, hydroxypyridine, metal salts of benzoic acid, and hydroxypyridine ARCH CHEMICALS, INC. (US) 2008-10-14 US disclosed
EP-1954753-A2 PAINT CONTAINING METAL SALT OF PYRITHIONE AND CUPROUX OXIDE Arch Chemicals, Inc. (US) 2008-08-13 EP disclosed
WO-2007061546-A2 PAINT CONTAINING METAL SALT OF PYRITHIONE AND CUPROUX OXIDE ARCH CHEMICALS, INC. (US) 2007-05-31 WO disclosed
US-20070117895-A1 Stabilized against viscosity change, gelation and agglomeration during formulation and storage; storage stability, gel-free; hydrolysable acrylate resin selected from copper acrylate, zinc acrylate, silyl acrylate; benzoic acid, hydroxypyridine, metal salts of benzoic acid, and hydroxypyridine ARCH CHEMICALS, INC. 2007-05-24 US disclosed