SCHEMBL5164656

SCHEMBL5164656

C=C(C(=O)O)[Si](CCCCC)(CCCCC)CCCCC

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AKR1B1 P15121 1/20 0.39
GPR84 Q9NQS5 7/20 0.38
PPARG P37231 7/20 0.38
PPARD Q03181 7/20 0.38
PPARA Q07869 7/20 0.38
HDAC11 Q96DB2 5/20 0.38
TSHR P16473 4/20 0.38
PTPN1 P18031 3/20 0.38
ALDH1A1 P00352 2/20 0.38
TLR2 O60603 2/20 0.38
TDP1 Q9NUW8 2/20 0.38
FABP4 P15090 2/20 0.38
SLC22A6 Q4U2R8 1/20 0.38
SLC22A8 Q8TCC7 1/20 0.38
MEN1 O00255 1/20 0.38
ESR1 P03372 1/20 0.38
ALOX15 P16050 1/20 0.38
PDE4A P27815 1/20 0.38
KMT2A Q03164 1/20 0.38
PDE3A Q14432 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4830323 0.98 GPR84 (0.41) GPR84PPARGPPARDPPARAHDAC11
SCHEMBL4834591 0.98 GPR84 (0.41) GPR84PPARGPPARDPPARAHDAC11
SCHEMBL4832778 0.93 AKR1B1 (0.36) AKR1B1GPR84PPARGPPARDPPARA
SCHEMBL4832840 0.84 FFAR3 (0.32)
SCHEMBL4832765 0.74 FFAR3 (0.33)
SCHEMBL5163345 0.71 THRB (0.37) AKR1B1GPR84PPARGPPARDPPARA
Methacrylic Acid SCHEMBL1140479 0.71 TSHR (0.52) AKR1B1GPR84PPARGPPARDPPARA
Methacrylic Acid SCHEMBL4642347 0.71 TSHR (0.52) AKR1B1GPR84PPARGPPARDPPARA
Hexane SCHEMBL29961959 0.69 AKR1B1 (0.61) AKR1B1GPR84PPARGPPARDPPARA
Hexane SCHEMBL27424892 0.69 AKR1B1 (0.61) AKR1B1GPR84PPARGPPARDPPARA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7297727-B2 Triarylsilyl(meth)acryloyl-containing polymers for marine coating compositions ARKEMA INC. (US) 2007-11-20 US disclosed
EP-1479737-B1 Triarylsilyl(meth)acryloyl-containing polymers for marine coating compositions ARKEMA INC (US) 2006-08-16 EP disclosed
EP-1479737-A1 Triarylsilyl(meth)acryloyl-containing polymers for marine coating compositions Atofina Chemicals, Inc. (US) 2004-11-24 EP disclosed
US-20040138332-A1 Triarylsilyl(meth)acryloyl-containing polymers for marine coating compositions ARKEMA INC. 2004-07-15 US disclosed
US-20030225184-A1 Triarylsilyl(meth)acryloyl-containing polymers for marine coating compositions ARKEMA INC. 2003-12-04 US disclosed
EP-1367100-A1 Triarylsilyl (meth) acryloyl-containing polymers for marine coating compositions ATOFINA CHEMICALS, INC. (US) 2003-12-03 EP disclosed