Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | ORAI1 | Q96D31 | 1/20 | 0.36 |
| ▸ | ORAI2 | Q96SN7 | 1/20 | 0.36 |
| ▸ | ORAI3 | Q9BRQ5 | 1/20 | 0.36 |
| ▸ | TRPV6 | Q9H1D0 | 1/20 | 0.36 |
| ▸ | WDR5 | P61964 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | PARP1 | P09874 | 1/20 | 0.34 |
| ▸ | PYCR1 | P32322 | 1/20 | 0.34 |
| ▸ | ENPP2 | Q13822 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.33 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.33 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.33 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.33 |
| ▸ | SLC22A3 | O75751 | 1/20 | 0.33 |
| ▸ | HTR3B | O95264 | 1/20 | 0.33 |
| ▸ | PLAU | P00749 | 1/20 | 0.33 |
| ▸ | HTR3A | P46098 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1138514 | 0.76 | ORAI1 (0.54) | TSHRORAI1ORAI2ORAI3TRPV6 | |
| SCHEMBL11815 | 0.76 | ENPP2 (0.56) | TSHRORAI1ORAI2ORAI3TRPV6 | |
| SCHEMBL24871112 | 0.72 | TSHR (0.44) | TSHRORAI1ORAI2ORAI3TRPV6 | |
| SCHEMBL1193871 | 0.71 | — | — | |
| Boric Acid SCHEMBL2464491 | 0.70 | TSHR (0.57) | TSHRALDH1A1PARP1ENPP2MEN1 | |
| Ethylene Glycol SCHEMBL5256026 | 0.69 | ENPP2 (0.53) | TSHRALDH1A1ENPP2 | |
| SCHEMBL16716648 | 0.68 | TSHR (0.40) | TSHRORAI1ORAI2ORAI3TRPV6 | |
| SCHEMBL1187173 | 0.68 | TSHR (0.40) | TSHRORAI1ORAI2ORAI3TRPV6 | |
| SCHEMBL7461964 | 0.68 | TSHR (0.40) | TSHRORAI1ORAI2ORAI3TRPV6 | |
| SCHEMBL4437860 | 0.68 | CYP3A4 (0.41) | TSHRORAI1ORAI2ORAI3TRPV6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2757197-A2 | Retroreflective elements and articles | 3M Innovative Properties Company (US) | 2014-07-23 | — | — | EP | disclosed |
| EP-1709252-B1 | RETROREFLECTIVE ELEMENTS AND ARTICLES | 3M INNOVATIVE PROPERTIES CO (US) | 2014-03-26 | — | — | EP | disclosed |
| CN-100541240-C | Retroreflective elements and pavement markers | 3M INNOVATIVE PROPERTIES CO (US) | 2009-09-16 | — | — | CN | disclosed |
| US-7458693-B2 | Retroreflective elements and articles | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2008-12-02 | — | — | US | disclosed |
| US-7413316-B2 | Retroreflective elements and articles | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2008-08-19 | — | — | US | disclosed |
| US-20080145146-A1 | RETROREFLECTIVE ELEMENTS AND ARTICLES | 3M INNOVATIVE PROPERTIES COMPANY | 2008-06-19 | — | — | US | disclosed |
| US-20070206285-A1 | RETROREFLECTIVE ELEMENTS AND ARTICLES | 3M INNOVATIVE PROPERTIES COMPANY | 2007-09-06 | — | — | US | disclosed |
| CN-1910322-A | Retroreflective elements and articles | 3M INNOVATIVE PROPERTIES CO (US) | 2007-02-07 | — | — | CN | disclosed |
| US-7168815-B2 | Retroreflective elements and articles | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2007-01-30 | — | — | US | disclosed |
| US-7156528-B2 | Retroreflective elements and articles | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2007-01-02 | — | — | US | disclosed |
| EP-1709252-A1 | RETROREFLECTIVE ELEMENTS AND ARTICLES | 3M Innovative Properties Company (US) | 2006-10-11 | — | — | EP | disclosed |
| WO-2005073468-A1 | RETROREFLECTIVE ELEMENTS AND ARTICLES | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2005-08-11 | — | — | WO | disclosed |
| US-20050157389-A1 | Retroreflective elements and articles | 3M INNOVATIVE PROPERTIES COMPANY | 2005-07-21 | — | — | US | disclosed |
| US-20050157390-A1 | Retroreflective elements and articles | 3M INNOVATIVE PROPERTIES COMPANY | 2005-07-21 | — | — | US | disclosed |