SCHEMBL48358

SCHEMBL48358

Sc1cccc(Cl)c1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18628556 0.97
Hydrogen Sulfide SCHEMBL27747276 0.97 ALDH1A1 (0.46)
Water SCHEMBL28356164 0.97
SCHEMBL5009584 0.84 TSHR (0.37)
Benzenethiol SCHEMBL27930544 0.83 TSHR (0.50)
SCHEMBL25720257 0.79 PNMT (0.52)
SCHEMBL7195051 0.78 CYP2A6 (0.41)
SCHEMBL63173 0.77
SCHEMBL28140 0.77
SCHEMBL28129975 0.77 TSHR (0.61)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 2640 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117466790-B Preparation method of alpha-sulfinylated carbonyl compound 西北师范大学 2024-05-28 CN claimed
CN-117586304-A Aryl phosphonate and aryl thiophosphonate compound and preparation method thereof 烟台大学 2024-02-23 CN claimed
CN-117466790-A Preparation method of alpha-sulfinylated carbonyl compound 西北师范大学 2024-01-30 CN claimed
CN-111606945-B Preparation method of compound containing P-O bond or P-S bond 烟台大学 2023-06-20 CN claimed
CN-112289937-B Quantum dot light-emitting diode and preparation method thereof TCL科技集团股份有限公司 2022-08-23 CN claimed
CN-113880739-A Synthesis method of polychlorinated diphenyl sulfide compound 安徽大学 2022-01-04 CN claimed
US-11077339-B1 Golf ball SCANNA CO., LTD. (TW) 2021-08-03 US claimed
CN-110698456-B Synthesis method of 2, 3-dihydrothiochromen-4-one and derivatives thereof 重庆医药高等专科学校 2021-05-14 CN claimed
CN-110452204-B Xanthatin thioether and imine derivatives, and preparation method and application thereof 山西农业大学 2021-03-12 CN claimed
CN-112289937-A Quantum dot light-emitting diode and preparation method thereof TCL集团股份有限公司 2021-01-29 CN claimed
US-20030134955-A1 Polybutadiene rubber composition comprising a halogenated organosulfur compound or a metal salt thereof JPMORGAN CHASE BANK, N.A., AS SUCCESSOR ADMINISTRATIVE AGENT 2003-07-17 US claimed
US-20030130396-A1 Golf ball cores comprising a halogenated organosulfur compound ACUSHNET COMPANY 2003-07-10 US claimed
US-20030119989-A1 Low compression, resilient golf balls with rubber core ACUSHNET COMPANY 2003-06-26 US claimed
US-20030114249-A1 Golf ball core compositions comprising unsaturated long chain organic acids and their salts JPMORGAN CHASE BANK, N.A., AS SUCCESSOR ADMINISTRATIVE AGENT 2003-06-19 US claimed
CN-1420864-A Process for producing bishalophenyl disulfide SUMITOMO SEIKA CHEMICALS (JP) 2003-05-28 CN claimed
US-20030064826-A1 Golf ball cores comprising a halogenated organosulfur compound JPMORGAN CHASE BANK, N.A., AS SUCCESSOR ADMINISTRATIVE AGENT 2003-04-03 US claimed
US-20030060665-A1 Process for producing bishalophenyl disulfide SUMITOMO SEIKA CHEMICALS CO., LTD. (JP) 2003-03-27 US claimed
EP-1277731-A1 PROCESS FOR PRODUCING BISHALOPHENYL DISULFIDE SUMITOMO SEIKA CHEMICALS CO., LTD. (JP) 2003-01-22 EP claimed
US-20020098915-A1 Thin, thermoset, polyurethane-covered golf ball with a dual core JPMORGAN CHASE BANK, N.A., AS SUCCESSOR ADMINISTRATIVE AGENT 2002-07-25 US claimed
US-4282246-A Antidiabetic furancarboxylic and thiphenecarboxylic acids PFIZER INC. (US) 1981-08-04 US claimed