Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.60 |
| ▸ | CYP4F2 | P78329 | 2/20 | 0.59 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.59 |
| ▸ | MEN1 | O00255 | 3/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.56 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.54 |
| ▸ | RAB9A | P51151 | 2/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.53 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | SENP1 | Q9P0U3 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.49 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16706893 | 0.86 | LOXL2 (0.62) | LOXL2CYP4F2CYP4A11SLC7A5ALDH1A1 | |
| SCHEMBL165622 | 0.86 | LOXL2 (0.66) | LOXL2CYP4F2CYP4A11MEN1KMT2A | |
| SCHEMBL13229122 | 0.85 | KMT2A (0.80) | LOXL2CYP4F2CYP4A11MEN1KMT2A | |
| SCHEMBL4836068 | 0.84 | MEN1 (0.63) | MEN1KMT2ARAB9ANPC1FOLH1 | |
| SCHEMBL1830055 | 0.82 | LOXL2 (0.54) | LOXL2CYP4F2CYP4A11MEN1KMT2A | |
| SCHEMBL10106423 | 0.81 | LOXL2 (0.64) | LOXL2CYP4F2CYP4A11SLC7A5ALDH1A1 | |
| SCHEMBL17882189 | 0.81 | RIPK1 (0.64) | LOXL2CYP4F2CYP4A11SLC7A5ALDH1A1 | |
| SCHEMBL3124357 | 0.80 | LOXL2 (0.55) | LOXL2CYP4F2CYP4A11SLC7A5ALDH1A1 | |
| SCHEMBL7087183 | 0.79 | MEN1 (0.54) | MEN1KMT2ARAB9ANPC1 | |
| SCHEMBL29592260 | 0.79 | LOXL2 (0.70) | LOXL2CYP4F2CYP4A11MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080255109-A1 | Non-peptide GnRH antagonists | VANTIA, LTD | 2008-10-16 | — | — | US | disclosed |
| US-7365065-B2 | Non-peptide GnRH antagonists | FERRING B.V. (NL) | 2008-04-29 | — | — | US | disclosed |
| US-20050222139-A1 | Non-peptide gnrh antagonists | FERRING B.V. (NL) | 2005-10-06 | — | — | US | disclosed |
| EP-1485356-A1 | NON-PEPTIDE GnRH ANTAGONISTS | Ferring BV (NL) | 2004-12-15 | — | — | EP | disclosed |
| WO-2003078398-A1 | NON-PEPTIDE GnRH ANTAGONISTS | FERRING BV (NL) | 2003-09-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050222139-A1 | Non-peptide gnrh antagonists | GNRHR, BRS3, FSHR | LOXL2 4042/4885CYP4F2 487/4885CYP4A11 241/4885 |
| US-20080255109-A1 | Non-peptide GnRH antagonists | GNRHR, BRS3, FSHR | LOXL2 3789/4885CYP4F2 486/4885CYP4A11 244/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.