Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 1/20 | 0.42 |
| ▸ | MAPK10 | P53779 | 4/20 | 0.41 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | EIF2AK1 | Q9BQI3 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | LCK | P06239 | 1/20 | 0.37 |
| ▸ | BTK | Q06187 | 1/20 | 0.37 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.37 |
| ▸ | KDM1A | O60341 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL4109058 | 0.99 | P2RX7 (0.43) | P2RX7MAPK10MAPK14ACHELMNA | |
| SCHEMBL4772235 | 0.92 | ACHE (0.43) | P2RX7ACHELMNAMAPTMEN1 | |
| Hydrochloric Acid SCHEMBL4096507 | 0.91 | ACHE (0.42) | P2RX7ACHELMNAMAPTDNMT1 | |
| Hydrochloric Acid SCHEMBL4113907 | 0.85 | P2RX7 (0.42) | P2RX7MAPK10MAPK14ACHELMNA | |
| Hydrochloric Acid SCHEMBL4104346 | 0.85 | P2RX7 (0.42) | P2RX7MAPK10MAPK14ACHELMNA | |
| SCHEMBL4770232 | 0.83 | P2RX7 (0.39) | P2RX7MAPK10MAPK14ACHELMNA | |
| SCHEMBL4770298 | 0.83 | SMN1; SMN2 (0.39) | P2RX7MAPK10MAPK14ACHELMNA | |
| Hydrochloric Acid SCHEMBL4103184 | 0.83 | P2RX7 (0.40) | P2RX7MAPK10MAPK14ACHELMNA | |
| SCHEMBL4770228 | 0.83 | SMN1; SMN2 (0.39) | P2RX7MAPK10MAPK14ACHELMNA | |
| Hydrochloric Acid SCHEMBL4107067 | 0.82 | P2RX7 (0.40) | P2RX7MAPK10MAPK14ACHELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1896419-A1 | 3,4-DIHYDROISOQUINOLINIUM SALT DERIVATIVES | HANWHA CHEMICAL CORPORATION (KR) | 2008-03-12 | — | — | EP | disclosed |
| WO-2006129978-A1 | 3,4-DIHYDROISOQUINOLINIUM SALT DERIVATIVES | HANWHA CHEMICAL CORPORATION (KR) | 2006-12-07 | — | — | WO | disclosed |