3-Methyladenine

3-Methyladenine

SCHEMBL48369

Cn1cnc(N)c2ncnc1-2

nearest known ligand 0.46

Full drug profile on Sugi Atlas →

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
ADORA2A P29274 10/20 0.46
ADORA1 P30542 7/20 0.46
PI4KA P42356 5/20 0.36
PI4K2B Q8TCG2 5/20 0.36
PI4K2A Q9BTU6 5/20 0.36
PI4KB Q9UBF8 5/20 0.36
TEK Q02763 3/20 0.35
FLT1 P17948 2/20 0.35
KDR P35968 2/20 0.35
CDK1 P06493 1/20 0.34
DYRK1A Q13627 1/20 0.33
ADORA2B P29275 4/20 0.33
YTHDC1 Q96MU7 1/20 0.32
XDH P47989 1/20 0.30
ADORA3 P0DMS8 1/20 0.30
EGFR P00533 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
3-Methyladenine SCHEMBL18229771 0.78 ADORA2A (0.34) ADORA2AADORA1
3-Methyladenine SCHEMBL18229772 0.78 PI4KA (0.35) ADORA2AADORA1PI4KAPI4K2BPI4K2A
3-Propyladenine SCHEMBL15756434 0.76 ADORA2A (0.53) ADORA2AADORA1PI4KAPI4K2BPI4K2A
SCHEMBL6674435 0.75 ADORA2A (0.33) ADORA2AADORA1YTHDC1
SCHEMBL17371772 0.75
SCHEMBL1882911 0.75
SCHEMBL19522164 0.75 ADORA2A (0.50) ADORA2AADORA1PI4KAPI4K2BPI4K2A
3-Ethyladenine SCHEMBL48200 0.75 ADORA2A (0.50) ADORA2AADORA1PI4KAPI4K2BPI4K2A
SCHEMBL15974909 0.75 ADORA2A (0.31) ADORA2AADORA1
SCHEMBL9108201 0.72 ADORA2A (0.36) ADORA2AADORA1PI4KAPI4K2BPI4K2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 5744 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4747627-A1 METHODS AND SYSTEMS FOR PREDICTIVE CLASSIFICATION BY MASS SPECTROMETRY AND TRAINED LARGE SPECTRAL MODELS Matterworks Inc (US) 2026-05-27 EP claimed
CN-122075438-A Synergistic anticancer application of redox responsive coacervate delivery chrysin and 3-methyladenine 2026-05-26 CN claimed
EP-4297723-B1 MICRONEEDLE COMPOSITIONS AND METHODS OF DELIVERY USING THE SAME BRIGHAM & WOMENS HOSPITAL INC (US) 2026-05-20 EP claimed
US-12630851-B2 Polynucleotide modification methods OXFORD NANOPORE TECHNOLOGIES PLC (GB) 2026-05-19 US claimed
US-20260098287-A1 METHOD AND KIT FOR REGENERATING REUSABLE INITIATORS FOR NUCLEIC ACID SYNTHESIS CHENG-YAO CHEN (TW) 2026-04-09 US claimed
US-20250369027-A1 SUBSTRATE CLEAVAGE FOR NUCLEIC ACID SYNTHESIS TWIST BIOSCIENCE CORP (US) 2025-12-04 US claimed
US-12478685-B2 Methods and kits for identifying subjects responsive to arginine deprivation therapy POLARIS PHARMACEUTICALS. INC. (US) 2025-11-25 US claimed
US-12458630-B2 Combination therapy for cancer THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2025-11-04 US claimed
US-20250327068-A1 Method for Generation of a Nucleic Acid Library MILTENYI BIOTEC BV & CO KG (DE) 2025-10-23 US claimed
EP-4618997-A1 COMPOSITIONS AND METHODS FOR IMPROVED CANCER TREATMENT The Council of the Queensland Institute of Medical Research (AU) 2025-09-24 EP claimed
WO-1999025385-A1 A METHOD OF INCREASING NUCLEIC ACID SYNTHESIS WITH ULTRASOUND IMARX PHARMACEUTICAL CORP. (US) 1999-05-27 WO claimed
WO-1998041648-A9 TARGET GENES FOR ALLELE-SPECIFIC DRUGS 1999-01-07 WO claimed
WO-1998041648-A2 TARGET GENES FOR ALLELE-SPECIFIC DRUGS VARIAGENICS, INC. (US) 1998-09-24 WO claimed
WO-1998039334-A1 DNA GLYCOSYLASE INHIBITORS, AND USES RELATED THERETO PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) 1998-09-11 WO claimed
US-5659348-A APPLYING TO A SUBSTRATE XEROX CORPORATION (US) 1997-08-19 US claimed
EP-0743573-A2 Method for obtaining image contrast migration imaging members XEROX CORPORATION (US) 1996-11-20 EP claimed
EP-0743574-A2 Migration imaging members XEROX CORPORATION (US) 1996-11-20 EP claimed
US-5563014-A SOFTENABLE LAYER CONTAINIG PHOTOSENSITIVE MARKING MATERIAL; TRANSPARENTIZING AGENT XEROX CORPORATION (US) 1996-10-08 US claimed
US-5514505-A SELECTIVE TRANSPARENTIZATION OF PHOTOSENSITIVE MIGRATION MARKING PARTICLES EMBEDDED NEAR THE SURFACE OF A SOFTENABLE LAYER SUPPORTED BY AN ELECTROCONDUCTIVE SUBSTRATE XEROX CORPORATION (US) 1996-05-07 US claimed
EP-0673783-A2 Recording sheets containing purine, pyrimidine, benzimidazole, imidazolidine, urazole, pyrazole, triazole, benzotriazole, tetrazole, and pyrazine compounds XEROX CORPORATION (US) 1995-09-27 EP claimed