Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 12/20 | 0.36 |
| ▸ | ADORA1 | P30542 | 4/20 | 0.36 |
| ▸ | PI4KA | P42356 | 3/20 | 0.36 |
| ▸ | PI4K2B | Q8TCG2 | 3/20 | 0.36 |
| ▸ | PI4K2A | Q9BTU6 | 3/20 | 0.36 |
| ▸ | PI4KB | Q9UBF8 | 3/20 | 0.36 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | AHCY | P23526 | 5/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5513295 | 0.83 | ADORA2A (0.35) | ADORA2AADORA1PI4KAPI4K2BPI4K2A | |
| 3-Propyladenine SCHEMBL15756434 | 0.80 | ADORA2A (0.53) | ADORA2AADORA1PI4KAPI4K2BPI4K2A | |
| SCHEMBL170695 | 0.79 | ADORA2A (0.41) | ADORA2AADORA1PI4KAPI4K2BPI4K2A | |
| 3-Benzyladenine SCHEMBL5352368 | 0.76 | ADORA2A (0.56) | ADORA2API4KAPI4K2BPI4K2API4KB | |
| SCHEMBL11076308 | 0.75 | AHCY (0.57) | ADORA2AADORA1PI4KAPI4K2BPI4K2A | |
| SCHEMBL21121744 | 0.75 | SMN1; SMN2 (0.47) | ADORA2API4KAPI4K2BPI4K2API4KB | |
| SCHEMBL21121625 | 0.75 | ADORA2A (0.41) | ADORA2API4KAPI4K2BPI4K2API4KB | |
| SCHEMBL21121959 | 0.75 | KCNH2 (0.44) | ADORA2API4KAPI4K2BPI4K2API4KB | |
| SCHEMBL21121675 | 0.74 | ALDH1A1 (0.46) | ADORA2AADORA1PI4KAPI4K2BPI4K2A | |
| SCHEMBL21121650 | 0.74 | ADORA2A (0.40) | ADORA2API4KAPI4K2BPI4K2API4KB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0630381-A4 | ANTIVIRAL ACYCLIC PHOSPHONOMETHOXYALKYL SUBSTITUTED, ALKENYL AND ALKYNYL PURINE AND PYRIMIDINE DERIVATIVES. | — | 1995-01-04 | — | — | EP | disclosed |
| EP-0630381-A1 | ANTIVIRAL ACYCLIC PHOSPHONOMETHOXYALKYL SUBSTITUTED, ALKENYL AND ALKYNYL PURINE AND PYRIMIDINE DERIVATIVES. | ACAD OF SCIENCE CZECH REPUBLIC (CS) | 1994-12-28 | — | — | EP | disclosed |