SCHEMBL6674435

SCHEMBL6674435

Cn1cnc(O)c2ncnc1-2

nearest known ligand 0.33

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
ADORA2A P29274 1/20 0.33
ADORA1 P30542 1/20 0.33
YTHDC1 Q96MU7 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
3-Methyladenine SCHEMBL48369 0.75 ADORA2A (0.46) ADORA2AADORA1YTHDC1
SCHEMBL9294950 0.69 KDM4E (0.34)
SCHEMBL6674163 0.68 SMN1; SMN2 (0.33) ADORA2AADORA1
SCHEMBL10379715 0.67 MAOA (0.33) ADORA2AADORA1
SCHEMBL2115745 0.67 ADORA2A (0.33) ADORA2AADORA1YTHDC1
SCHEMBL6675394 0.65 ADORA2A (0.46) ADORA2A
SCHEMBL2414858 0.62 ADORA2A (0.40) ADORA2AADORA1YTHDC1
SCHEMBL4734999 0.62 ADORA1 (0.60) ADORA2AADORA1YTHDC1
SCHEMBL574806 0.60 LTA4H (0.39) ADORA2AADORA1
SCHEMBL1914 0.58 ADORA2A (0.41) ADORA2AADORA1YTHDC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1202628-A4 NOVEL HYPOXANTHINE AND THIOHYPOXANTHINE COMPOUNDS EURO CELTIQUE SA (LU) 2002-10-30 EP claimed
EP-1202628-A1 NOVEL HYPOXANTHINE AND THIOHYPOXANTHINE COMPOUNDS Euro-Celtique S.A. (LU) 2002-05-08 EP claimed
WO-2001011967-A1 NOVEL HYPOXANTHINE AND THIOHYPOXANTHINE COMPOUNDS EURO-CELTIQUE S.A. (LU) 2001-02-22 WO claimed
EP-1202628-B1 NOVEL HYPOXANTHINE AND THIOHYPOXANTHINE COMPOUNDS EURO CELTIQUE SA (LU) 2004-10-13 EP disclosed
EP-1202628-A4 NOVEL HYPOXANTHINE AND THIOHYPOXANTHINE COMPOUNDS EURO CELTIQUE SA (LU) 2002-10-30 EP disclosed
EP-1202628-A1 NOVEL HYPOXANTHINE AND THIOHYPOXANTHINE COMPOUNDS Euro-Celtique S.A. (LU) 2002-05-08 EP disclosed
WO-2001011967-A1 NOVEL HYPOXANTHINE AND THIOHYPOXANTHINE COMPOUNDS EURO-CELTIQUE S.A. (LU) 2001-02-22 WO disclosed