Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 1/20 | 0.46 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.36 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.36 |
| ▸ | PI4KA | P42356 | 1/20 | 0.36 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.36 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.36 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.36 |
| ▸ | HTR7 | P34969 | 9/20 | 0.33 |
| ▸ | HTR1A | P08908 | 6/20 | 0.33 |
| ▸ | HTR6 | P50406 | 9/20 | 0.33 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.33 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.33 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.31 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8830778 | 0.81 | LTA4H (0.47) | LTA4HADORA2ACYP3A4CYP2C9CYP2C19 | |
| SCHEMBL48312 | 0.79 | LTA4H (0.45) | LTA4H | |
| SCHEMBL5675147 | 0.77 | LTA4H (0.43) | LTA4H | |
| SCHEMBL27990888 | 0.75 | LTA4H (0.45) | LTA4H | |
| SCHEMBL13004006 | 0.71 | LTA4H (0.47) | LTA4HADORA2AADORA1PI4KAPI4K2B | |
| SCHEMBL2308094 | 0.70 | — | — | |
| SCHEMBL28318172 | 0.70 | LTA4H (0.49) | LTA4HCYP3A4CYP2C9CYP2C19 | |
| SCHEMBL1535169 | 0.69 | LTA4H (0.36) | LTA4H | |
| SCHEMBL6639614 | 0.69 | LTA4H (0.36) | LTA4H | |
| SCHEMBL276781 | 0.69 | LTA4H (0.36) | LTA4H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10900071-B2 | Identification of genetic modifications | WAKE FOREST UNIVERSITY HEALTH SCIENCES (US) | 2021-01-26 | — | — | US | disclosed |
| US-20190040457-A1 | IDENTIFICATION OF GENETIC MODIFICATIONS | WAKE FOREST UNIVERSITY HEALTH SCIENCES (US) | 2019-02-07 | — | — | US | disclosed |
| EP-3307755-A1 | IDENTIFICATION OF GENETIC MODIFICATIONS | Wake Forest University Health Sciences (US) | 2018-04-18 | — | — | EP | disclosed |
| WO-2016183289-A1 | IDENTIFICATION OF GENETIC MODIFICATIONS | WAKE FOREST UNIVERSITY HEALTH SERVICES (US) | 2016-11-17 | — | — | WO | disclosed |
| EP-2028272-B1 | METHOD OF MODIFYING NUCLEOTIDE CHAIN | PANASONIC CORP (JP) | 2014-01-08 | — | — | EP | disclosed |
| US-8129115-B2 | Method of modifying nucleotide chain | PANASONIC CORPORATION (JP) | 2012-03-06 | — | — | US | disclosed |
| US-20100291637-A1 | METHOD FOR MODIFYING NUCLEOTIDE CHAIN | PANASONIC CORPORATION (JP) | 2010-11-18 | — | — | US | disclosed |
| US-20100015670-A1 | METHOD OF MODIFYING NUCLEOTIDE CHAIN | PANASONIC CORPORATION (JP) | 2010-01-21 | — | — | US | disclosed |
| EP-1647592-B1 | METHOD OF MODIFYING NUCLEOTIDE CHAIN | PANASONIC CORP (JP) | 2009-03-11 | — | — | EP | disclosed |
| EP-2028272-A1 | METHOD OF MODIFYING NUCLEOTIDE CHAIN | Panasonic Corporation (JP) | 2009-02-25 | — | — | EP | disclosed |
| US-20070077629-A1 | Method for modifying nucleotide chain | PANASONIC CORPORATION (JP) | 2007-04-05 | — | — | US | disclosed |
| EP-1647592-A1 | METHOD OF MODIFYING NUCLEOTIDE CHAIN | MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) | 2006-04-19 | — | — | EP | disclosed |