SCHEMBL5675147

SCHEMBL5675147

C=CCn1cncc2ncnc1-2

nearest known ligand 0.43

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
LTA4H P09960 1/20 0.43
NPC1 O15118 1/20 0.33
HPGD P15428 1/20 0.33
RAB9A P51151 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
ADORA2B P29275 1/20 0.32
NPSR1 Q6W5P4 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8878534 0.74 LTA4H (0.43) LTA4HNPC1HPGDRAB9ASMN1; SMN2
SCHEMBL27364397 0.74
SCHEMBL1740944 0.73 LTA4H (0.34) LTA4H
Iodide SCHEMBL27303018 0.72 CYP19A1 (0.41) ADORA2B
SCHEMBL48312 0.71 LTA4H (0.45) LTA4H
SCHEMBL5779690 0.68
SCHEMBL9497797 0.68 ADORA2B (0.33) ADORA2B
SCHEMBL27990888 0.68 LTA4H (0.45) LTA4H
SCHEMBL170695 0.68 ADORA2A (0.41) NPC1HPGDRAB9ASMN1; SMN2ADORA2B
SCHEMBL2053090 0.67 AVPR2 (0.32) ADORA2B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20060141523-A1 Integrated method for PCR cleanup and oligonucleotide removal APPLERA CORPORATION (US) 2006-06-29 US disclosed
EP-1330546-B1 METHOD FOR THE AMPLIFICATION AND OPTIONAL CHARACTERISATION OF NUCLEIC ACIDS UNIV COLLEGE CORK NAT UNIV IE (IE) 2006-01-11 EP disclosed
US-20040067559-A1 Method for the amplification and optional characterisation of nucleic acids UNIVERSITY COLLEGE-CORK NATIONAL UNIVERSITY OF IRELAND (IE) 2004-04-08 US disclosed
EP-1330546-A2 METHOD FOR THE AMPLIFICATION AND OPTIONAL CHARACTERISATION OF NUCLEIC ACIDS University College Cork-National University of Ireland, Cork (IE) 2003-07-30 EP disclosed
WO-2002036821-A2 METHOD FOR THE AMPLIFICATION AND OPTIONAL CHARACTERISATION OF NUCLEIC ACIDS UNIVERSITY COLLEGE CORK - NATIONAL UNIVERSITY OF IRELAND, CORK; (IE) 2002-05-10 WO disclosed