Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | TSHR | P16473 | 4/20 | 0.43 |
| ▸ | SPHK1 | Q9NYA1 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.35 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.35 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | HTR2C | P28335 | 1/20 | 0.35 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.35 |
| ▸ | HRH1 | P35367 | 1/20 | 0.35 |
| ▸ | DRD3 | P35462 | 1/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.33 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.33 |
| ▸ | FDPS | P14324 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4838489 | 0.91 | LMNA (0.48) | LMNATSHRSPHK1TDP1CHRM1 | |
| SCHEMBL230925 | 0.88 | LMNA (0.44) | LMNATSHRSPHK1TDP1CHRM1 | |
| SCHEMBL19770596 | 0.88 | LMNA (0.44) | LMNATSHRSPHK1TDP1CHRM1 | |
| SCHEMBL28350636 | 0.84 | SPHK1 (0.61) | LMNASPHK1CYP3A4TRPV1TRPA1 | |
| SCHEMBL13476921 | 0.82 | LMNA (0.55) | LMNATSHRSPHK1TDP1CHRM1 | |
| SCHEMBL104878 | 0.82 | LMNA (0.55) | LMNATSHRSPHK1TDP1CHRM1 | |
| SCHEMBL4382435 | 0.81 | SPHK1 (0.52) | LMNASPHK1CYP3A4TRPV1FDPS | |
| SCHEMBL1301102 | 0.80 | — | — | |
| SCHEMBL1301003 | 0.80 | — | — | |
| SCHEMBL19125432 | 0.80 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109180843-B | Non-phthalate compounds as electron donors for polyolefin catalysts | 美国台塑公司 | 2022-03-01 | — | — | CN | claimed |
| CN-110407963-B | Catalyst component for olefin polymerization and preparation method thereof | 中国石油化工股份有限公司 | 2021-09-21 | — | — | CN | claimed |
| CN-110407964-B | Catalyst component for olefin polymerization and preparation method thereof | 中国石油化工股份有限公司 | 2021-09-21 | — | — | CN | claimed |
| CN-104177520-B | It is used to prepare the ingredient of solid catalyst of olefin polymer | 中国石油化工股份有限公司 | 2018-06-12 | — | — | CN | claimed |
| EP-1472293-B1 | SOLID CATALYST COMPONENT FOR POLYMERIZATION OF OLEFINS, CATALYST COMPRISING THE SAME AND USE THEREOF | CHINA PETROLEUM & CHEM CORP (CN) | 2017-04-26 | — | — | EP | claimed |
| CN-104177521-B | Prepare method and the catalyst of solid catalyst component for olefine polymerization | 中国石油化工股份有限公司 | 2016-08-17 | — | — | CN | claimed |
| EP-2969201-B1 | NON-PHTHALATE COMPOUNDS AS ELECTRON DONORS FOR POLYOLEFIN CATALYSTS | FORMOSA PLASTICS CORP USA (US) | 2022-05-04 | — | — | EP | disclosed |
| CN-109180843-B | Non-phthalate compounds as electron donors for polyolefin catalysts | 美国台塑公司 | 2022-03-01 | — | — | CN | disclosed |
| CN-110407964-B | Catalyst component for olefin polymerization and preparation method thereof | 中国石油化工股份有限公司 | 2021-09-21 | — | — | CN | disclosed |
| CN-109180843-A | The non-phthalic acid ester compound as electron donor for polyolefin catalyst | 美国台塑公司 | 2019-01-11 | — | — | CN | disclosed |
| CN-105339085-B | Non-phthalate compounds as electron donors for polyolefin catalysts | 美国台塑公司 | 2018-06-26 | — | — | CN | disclosed |
| CN-104177520-B | It is used to prepare the ingredient of solid catalyst of olefin polymer | 中国石油化工股份有限公司 | 2018-06-12 | — | — | CN | disclosed |
| CN-104177521-B | Prepare method and the catalyst of solid catalyst component for olefine polymerization | 中国石油化工股份有限公司 | 2016-08-17 | — | — | CN | disclosed |
| CN-105712908-A | 1, 3-disulfonate compound for preparing olefin polymerization catalyst | 中国石油天然气股份有限公司 | 2016-06-29 | — | — | CN | disclosed |
| CN-105339085-A | Non-phthalate compounds as electron donors for polyolefin catalysts | FORMOSA PLASTICS CORP USA | 2016-02-17 | — | — | CN | disclosed |
| CN-104177520-A | Solid catalyst component for preparing olefin polymer | CHINA PETROLEUM & CHEMICAL | 2014-12-03 | — | — | CN | disclosed |
| CN-104177521-A | Method for preparing solid catalyst component for olefin polymerization and catalyst for olefin polymerization | CHINA PETROLEUM & CHEMICAL | 2014-12-03 | — | — | CN | disclosed |
| US-7388061-B2 | Solid catalyst component for polymerization of olefins, catalyst comprising the same and use thereof | CHINA PETROLEUM & CHEMICAL CORPORATION (CN) | 2008-06-17 | — | — | US | disclosed |
| US-20050239636-A1 | Solid catalyst component for polymerization of olefins, catalyst comprising the same and use thereof | CHINA PETROLEUM & CHEMICAL CORPORATION (CN) | 2005-10-27 | — | — | US | disclosed |