SCHEMBL4838489

SCHEMBL4838489

CCCC(O)C(C)C(O)CC

nearest known ligand 0.48

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.48
TSHR P16473 2/20 0.40
SPHK1 Q9NYA1 1/20 0.34
TRPA1 O75762 1/20 0.31
CHRM1 P11229 1/20 0.31
AKR1A1 P14550 1/20 0.31
CHRM3 P20309 1/20 0.31
HTR2A P28223 1/20 0.31
HTR2C P28335 1/20 0.31
ADRA1A P35348 1/20 0.31
HRH1 P35367 1/20 0.31
DRD3 P35462 1/20 0.31
SLC6A3 Q01959 1/20 0.31
HDAC1 Q13547 1/20 0.31
HDAC2 Q92769 1/20 0.31
TDP1 Q9NUW8 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4837083 0.91 LMNA (0.48) LMNATSHRSPHK1TRPA1CHRM1
SCHEMBL13176705 0.85 TSHR (0.53) LMNATSHRSPHK1TRPA1TDP1
SCHEMBL13210319 0.85 TSHR (0.53) LMNATSHRSPHK1TRPA1TDP1
SCHEMBL16817197 0.85 TSHR (0.53) LMNATSHRSPHK1TRPA1TDP1
SCHEMBL13210409 0.85 TSHR (0.53) LMNATSHRSPHK1TRPA1TDP1
SCHEMBL4831130 0.85 TSHR (0.53) LMNATSHRSPHK1TRPA1TDP1
SCHEMBL4005967 0.84 SPHK1 (0.46) LMNATSHRSPHK1TRPA1TDP1
SCHEMBL15281708 0.81 LMNA (0.41) LMNATSHRSPHK1TRPA1
SCHEMBL10864142 0.81 TSHR (0.45) LMNATSHRTRPA1TDP1
SCHEMBL19770596 0.80 LMNA (0.44) LMNATSHRSPHK1TRPA1CHRM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109180843-B Non-phthalate compounds as electron donors for polyolefin catalysts 美国台塑公司 2022-03-01 CN claimed
CN-110407963-B Catalyst component for olefin polymerization and preparation method thereof 中国石油化工股份有限公司 2021-09-21 CN claimed
CN-110407964-B Catalyst component for olefin polymerization and preparation method thereof 中国石油化工股份有限公司 2021-09-21 CN claimed
EP-1472293-B1 SOLID CATALYST COMPONENT FOR POLYMERIZATION OF OLEFINS, CATALYST COMPRISING THE SAME AND USE THEREOF CHINA PETROLEUM & CHEM CORP (CN) 2017-04-26 EP claimed
CN-109180843-B Non-phthalate compounds as electron donors for polyolefin catalysts 美国台塑公司 2022-03-01 CN disclosed
CN-110407964-B Catalyst component for olefin polymerization and preparation method thereof 中国石油化工股份有限公司 2021-09-21 CN disclosed
CN-110407963-B Catalyst component for olefin polymerization and preparation method thereof 中国石油化工股份有限公司 2021-09-21 CN disclosed
US-7388061-B2 Solid catalyst component for polymerization of olefins, catalyst comprising the same and use thereof CHINA PETROLEUM & CHEMICAL CORPORATION (CN) 2008-06-17 US disclosed
US-20050239636-A1 Solid catalyst component for polymerization of olefins, catalyst comprising the same and use thereof CHINA PETROLEUM & CHEMICAL CORPORATION (CN) 2005-10-27 US disclosed