Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD4 | P21917 | 15/20 | 0.60 |
| ▸ | DRD2 | P14416 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | GLA | P06280 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.44 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4674469 | 1.00 | DRD4 (0.60) | DRD4DRD2ALDH1A1GLATP53 | |
| SCHEMBL4837172 | 1.00 | DRD4 (0.60) | DRD4DRD2ALDH1A1GLATP53 | |
| SCHEMBL13651762 | 0.94 | DRD4 (0.60) | DRD4DRD2ALDH1A1GLA | |
| SCHEMBL11591604 | 0.94 | DRD4 (0.60) | DRD4DRD2ALDH1A1GLA | |
| SCHEMBL11592157 | 0.86 | DRD4 (0.61) | DRD4DRD2ALDH1A1GLA | |
| SCHEMBL13651811 | 0.84 | ALDH1A1 (0.60) | DRD4DRD2ALDH1A1GLATP53 | |
| SCHEMBL16923006 | 0.83 | ALDH1A1 (0.57) | DRD4ALDH1A1GLATP53CYP3A4 | |
| SCHEMBL7966930 | 0.83 | ALDH1A1 (0.54) | ALDH1A1GLATP53CYP3A4TSHR | |
| SCHEMBL7966929 | 0.83 | ALDH1A1 (0.54) | ALDH1A1GLATP53CYP3A4TSHR | |
| SCHEMBL7966936 | 0.83 | ALDH1A1 (0.54) | ALDH1A1GLATP53CYP3A4TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7642262-B2 | Arylipiperdinopropanol and arylipiperazinopropanol derivatives and pharmaceuticals containing the same | ASUBIO PHARMA CO., LTD. (JP) | 2010-01-05 | — | — | US | disclosed |
| US-7368608-B2 | 1-amido-3-(2-hydroxyphenoxy)-2-propanol derivatives and a process for preparing 2-amidomethyl-1,4-benzodioxane derivatives | DAISO CO., LTD. (JP) | 2008-05-06 | — | — | US | disclosed |
| US-20060019993-A1 | 1-Amido-3-(2-hydroxyphenoxy)-2-propanol derivatives and a process for preparing 2-amidomethyl-1,4-benzodioxane derivatives | DAISO CO., LTD. (JP) | 2006-01-26 | — | — | US | disclosed |
| US-4110472-A | CEREBROVASCULAR INSUFFICIENCY, PSYCHOSTIMULATION | BAYER AKTIENGESELLSCHAFT (DE) | 1978-08-29 | — | — | US | disclosed |
| US-4029795-A | 4(2' Isoquinolin-1-one)piperidines | CIBA-GEIGY CORPORATION (US) | 1977-06-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060019993-A1 | 1-Amido-3-(2-hydroxyphenoxy)-2-propanol derivatives and a process for preparing 2-amidomethyl-1,4-benzodioxane derivatives | CCNL2, CCNA1, CCNK | DRD4 713/4885DRD2 849/4885ALDH1A1 438/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.