Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | GLA | P06280 | 1/20 | 0.54 |
| ▸ | ACHE | P22303 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 11/20 | 0.50 |
| ▸ | MAPT | P10636 | 9/20 | 0.50 |
| ▸ | HPGD | P15428 | 5/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | USP2 | O75604 | 1/20 | 0.50 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | L3MBTL4 | Q8NA19 | 1/20 | 0.48 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.47 |
| ▸ | RAB9A | P51151 | 5/20 | 0.47 |
| ▸ | NPC1 | O15118 | 4/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7966930 | 1.00 | ALDH1A1 (0.54) | ALDH1A1GLAACHEL3MBTL1MAPT | |
| SCHEMBL7966929 | 1.00 | ALDH1A1 (0.54) | ALDH1A1GLAACHEL3MBTL1MAPT | |
| SCHEMBL27131262 | 0.92 | ALDH1A1 (0.59) | ALDH1A1GLAACHEL3MBTL1MAPT | |
| SCHEMBL15344472 | 0.89 | ACHE (0.45) | ALDH1A1GLAACHEL3MBTL1MAPT | |
| SCHEMBL15344471 | 0.89 | ACHE (0.45) | ALDH1A1GLAACHEL3MBTL1MAPT | |
| SCHEMBL31213024 | 0.85 | ALDH1A1 (0.64) | ALDH1A1GLAMAPTHPGDCYP2C9 | |
| SCHEMBL7953345 | 0.85 | ALDH1A1 (0.64) | ALDH1A1GLAL3MBTL1MAPTHPGD | |
| SCHEMBL262508 | 0.85 | ALDH1A1 (0.64) | ALDH1A1GLAL3MBTL1MAPTHPGD | |
| SCHEMBL7953349 | 0.85 | ALDH1A1 (0.64) | ALDH1A1GLAL3MBTL1MAPTHPGD | |
| SCHEMBL4945160 | 0.85 | ALDH1A1 (0.64) | ALDH1A1GLAMAPTHPGDCYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6242450-B1 | SUBSTITUTED PIPERIDINES | ELI LILLY AND COMPANY | 2001-06-05 | — | — | US | disclosed |
| WO-2000006082-A2 | TREATMENT OF ANXIETY DISORDERS | ELI LILLY AND COMPANY (US) | 2000-02-10 | — | — | WO | disclosed |
| WO-2000006166-A1 | 5-HT1F ANTAGONISTS | ELI LILLY AND COMPANY (US) | 2000-02-10 | — | — | WO | disclosed |
| EP-0976746-A1 | 5-HT1F antagonists | ELI LILLY AND COMPANY (US) | 2000-02-02 | — | — | EP | disclosed |
| EP-0976747-A2 | Use of 5HT-1F receptor antagonists for treating anxiety disorders | ELI LILLY AND COMPANY (US) | 2000-02-02 | — | — | EP | disclosed |
| EP-0718464-A1 | Well treatment using particulate blends | HALLIBURTON COMPANY (US) | 1996-06-26 | — | — | EP | disclosed |
| US-5492178-A | Well treating methods and devices using particulate blends | HALLIBURTON COMPANY (US) | 1996-02-20 | — | — | US | disclosed |
| US-5381864-A | Well treating methods using particulate blends | HALLIBURTON COMPANY (US) | 1995-01-17 | — | — | US | disclosed |