Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDPK1 | O15530 | 1/20 | 0.84 |
| ▸ | TTR | P02766 | 1/20 | 0.84 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.84 |
| ▸ | ABCB1 | P08183 | 13/20 | 0.73 |
| ▸ | MEN1 | O00255 | 1/20 | 0.69 |
| ▸ | LMNA | P02545 | 1/20 | 0.69 |
| ▸ | MAPT | P10636 | 1/20 | 0.69 |
| ▸ | MAOB | P27338 | 1/20 | 0.69 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.69 |
| ▸ | MGAM | O43451 | 1/20 | 0.64 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.59 |
| ▸ | DPP4 | P27487 | 1/20 | 0.59 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.59 |
| ▸ | RELA | Q04206 | 1/20 | 0.59 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.58 |
| ▸ | DHODH | Q02127 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Xanthogalenol SCHEMBL30259154 | 1.00 | PDPK1 (0.84) | PDPK1TTRALOX5ABCB1MEN1 | |
| Xanthogalenol SCHEMBL4837290 | 1.00 | PDPK1 (0.84) | PDPK1TTRALOX5ABCB1MEN1 | |
| SCHEMBL144848 | 0.92 | ABCB1 (0.85) | PDPK1TTRALOX5ABCB1MEN1 | |
| Xanthohumol SCHEMBL738122 | 0.91 | PDPK1 (1.00) | PDPK1TTRALOX5ABCB1MEN1 | |
| Xanthohumol SCHEMBL143683 | 0.91 | PDPK1 (1.00) | PDPK1TTRALOX5ABCB1MEN1 | |
| Xanthohumol SCHEMBL30169731 | 0.91 | PDPK1 (1.00) | PDPK1TTRALOX5ABCB1MEN1 | |
| SCHEMBL26539037 | 0.87 | PDPK1 (0.93) | PDPK1TTRALOX5ABCB1MEN1 | |
| SCHEMBL30630210 | 0.87 | PDPK1 (0.93) | PDPK1TTRALOX5ABCB1MEN1 | |
| Demethylxanthohumol SCHEMBL31051585 | 0.87 | MGAM (0.81) | PDPK1TTRALOX5ABCB1MEN1 | |
| Demethylxanthohumol SCHEMBL1023989 | 0.87 | MGAM (0.81) | PDPK1TTRALOX5ABCB1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7326734-B2 | Treatment of bladder and urinary tract cancers | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2008-02-05 | — | — | US | claimed |
| US-7326734-B2 | Treatment of bladder and urinary tract cancers | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2008-02-05 | — | — | US | disclosed |