Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 2/20 | 0.50 |
| ▸ | THRA | P10827 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | HRH1 | P35367 | 1/20 | 0.33 |
| ▸ | HTR2B | P41595 | 1/20 | 0.33 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.32 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6685103 | 0.78 | ESR1 (0.74) | ESR1THRATHRBSLC6A2HTR2A | |
| SCHEMBL4841322 | 0.75 | TP53 (0.42) | TAAR1 | |
| SCHEMBL4837546 | 0.74 | ESR1 (0.50) | ESR1THRATHRBSLC6A2HTR2A | |
| SCHEMBL21100336 | 0.71 | ESR1 (0.64) | ESR1THRATHRBSLC6A2HTR2A | |
| SCHEMBL4830207 | 0.70 | TSHR (0.46) | — | |
| SCHEMBL16978966 | 0.70 | ESR1 (0.56) | ESR1THRATHRBSLC6A2HTR2A | |
| SCHEMBL26192271 | 0.70 | ESR1 (0.56) | ESR1THRATHRBSLC6A2HTR2A | |
| SCHEMBL394340 | 0.69 | ESR1 (0.61) | ESR1THRATHRBSLC6A2HTR2A | |
| SCHEMBL15706822 | 0.69 | ESR1 (0.61) | ESR1THRATHRBSLC6A2HTR2A | |
| SCHEMBL861221 | 0.69 | ESR1 (0.61) | ESR1THRATHRBSLC6A2HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7378537-B2 | Olefin oligomerization catalysts and methods of using same | CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) | 2008-05-27 | — | — | US | disclosed |
| US-20080027188-A1 | OLEFIN OLIGOMERIZATION CATALYSTS AND METHODS OF USING SAME | CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) | 2008-01-31 | — | — | US | disclosed |