Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.36 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.36 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.36 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.35 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.34 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | GALR3 | O60755 | 1/20 | 0.34 |
| ▸ | BLM | P54132 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | MMP1 | P03956 | 1/20 | 0.33 |
| ▸ | MMP2 | P08253 | 1/20 | 0.33 |
| ▸ | MMP3 | P08254 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Butane SCHEMBL15233869 | 0.92 | LMNA (0.34) | TSHRCHRM2CHRM4CHRM1TBXA2R | |
| SCHEMBL609300 | 0.92 | RNPEP (0.44) | RNPEPSLC7A5LMNACYP19A1MMP1 | |
| SCHEMBL5476515 | 0.90 | TSHR (0.31) | TSHRCHRM2CHRM4CHRM1TBXA2R | |
| SCHEMBL2721210 | 0.87 | CYP19A1 (0.35) | TSHRCHRM2CHRM4CHRM1TBXA2R | |
| SCHEMBL5478887 | 0.86 | LMNA (0.35) | LMNA | |
| SCHEMBL13334330 | 0.85 | TSHR (0.31) | TSHRCHRM2CHRM4CHRM1TBXA2R | |
| SCHEMBL2991206 | 0.85 | TSHR (0.31) | TSHRCHRM2CHRM4CHRM1TBXA2R | |
| Biphenyl SCHEMBL17317281 | 0.82 | PDCD1 (0.50) | TSHRMAPTCYP2C9SMN1; SMN2 | |
| SCHEMBL14150381 | 0.82 | FAAH (0.37) | TSHRCHRM2CHRM4CHRM1TBXA2R | |
| SCHEMBL6078942 | 0.81 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7354977-B1 | Process for hydroxyalkylating carboxylic acid-functionalized materials | HENKEL CORPORATION (US) | 2008-04-08 | — | — | US | disclosed |
| EP-0973721-A4 | PROCESS FOR HYDROXYALKYLATING CARBOXYLIC ACID-FUNCTIONALIZED MATERIALS | LOCTITE CORP (US) | 2000-05-10 | — | — | EP | disclosed |
| EP-0973721-A1 | PROCESS FOR HYDROXYALKYLATING CARBOXYLIC ACID-FUNCTIONALIZED MATERIALS | LOCTITE CORPORATION (US) | 2000-01-26 | — | — | EP | disclosed |
| WO-1998031655-A1 | PROCESS FOR HYDROXYALKYLATING CARBOXYLIC ACID-FUNCTIONALIZED MATERIALS | LOCTITE CORPORATION (US) | 1998-07-23 | — | — | WO | disclosed |
| EP-0492237-A1 | Modified polyester resins, process for their preparation and toner containing these polyester resins | BAYER AG (DE) | 1992-07-01 | — | — | EP | disclosed |