Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 3/20 | 0.43 |
| ▸ | CES1 | P23141 | 3/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.42 |
| ▸ | NAAA | Q02083 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | SLC2A1 | P11166 | 2/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | ESR1 | P03372 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4838305 | 1.00 | CES2 (0.43) | CES2CES1PTGS2NAAAMEN1 | |
| SCHEMBL7455051 | 0.90 | HTR3A (0.41) | CES1NAAAMEN1KMT2AATM | |
| SCHEMBL7455048 | 0.90 | HTR3A (0.41) | CES1NAAAMEN1KMT2AATM | |
| SCHEMBL7455808 | 0.88 | PRSS1 (0.40) | NAAAATMALDH1A1 | |
| SCHEMBL7455813 | 0.88 | PRSS1 (0.40) | NAAAATMALDH1A1 | |
| SCHEMBL11384671 | 0.86 | ATM (0.42) | CES2CES1PTGS2MEN1KMT2A | |
| SCHEMBL7839283 | 0.86 | ATM (0.42) | CES2CES1PTGS2MEN1KMT2A | |
| SCHEMBL7458801 | 0.86 | HTR3A (0.41) | CES2CES1MEN1KMT2AATM | |
| SCHEMBL7458795 | 0.86 | HTR3A (0.41) | CES2CES1MEN1KMT2AATM | |
| SCHEMBL10993469 | 0.82 | SLC2A1 (0.43) | MEN1KMT2ASLC2A1ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1997834-A1 | Catalysts | Borealis Technology Oy (FI) | 2008-12-03 | — | — | EP | disclosed |