SCHEMBL483832

SCHEMBL483832

O=S(=O)(c1ccc(N=C=S)cc1)c1ccc(N=C=S)cc1

nearest known ligand 0.70

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 2/20 0.70
CA2 P00918 2/20 0.70
P2RY6 Q15077 3/20 0.50
MIF P14174 2/20 0.50
CYP3A4 P08684 4/20 0.47
HSD17B10 Q99714 3/20 0.47
ALDH1A1 P00352 3/20 0.47
MAPT P10636 3/20 0.47
KDM4E B2RXH2 2/20 0.47
USP2 O75604 2/20 0.47
LTA P01374 2/20 0.47
HPGD P15428 2/20 0.47
P2RX3 P56373 2/20 0.47
RAD51 Q06609 2/20 0.47
TDP1 Q9NUW8 2/20 0.47
CA9 Q16790 1/20 0.44
RAD1 O60671 1/20 0.43
PKM P14618 2/20 0.41
KEAP1 Q14145 2/20 0.41
NFE2L2 Q16236 2/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21378287 0.92 CA1 (0.61) CA1CA2P2RY6MIFCYP3A4
SCHEMBL23270212 0.87 CA1 (0.56) CA1CA2P2RY6MIFCYP3A4
SCHEMBL8694424 0.83 CA1 (0.66) CA1CA2P2RY6MIFCYP3A4
SCHEMBL668791 0.83 CA1 (0.66) CA1CA2P2RY6MIFCYP3A4
SCHEMBL1483567 0.83 CA1 (0.66) CA1CA2P2RY6MIFCYP3A4
SCHEMBL1476527 0.83 CA2 (1.00) CA1CA2P2RY6MIFALDH1A1
SCHEMBL2891113 0.83 CA1 (0.66) CA1CA2P2RY6MIFCYP3A4
SCHEMBL31315339 0.83 CA1 (0.66) CA1CA2P2RY6MIFCYP3A4
SCHEMBL6196292 0.83 CA1 (0.66) CA1CA2P2RY6MIFCYP3A4
SCHEMBL25891586 0.82 CA1 (0.50) CA1CA2P2RY6MIFCYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 227 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111534216-A Water-soluble triazinyl sulfone polyurethane and application thereof 湖南七纬科技有限公司 2020-08-14 CN claimed
CN-108977054-B Environment-friendly glass bottle baking varnish and preparation method thereof 江苏晶瑞玻璃有限公司 2020-08-14 CN claimed
CN-104531397-A Cleaning solution for sheet glass substrate thinning pre-cleaning, and application thereof HUIJING DISPLAY TECHNOLOGY SUZHOU CO LTD 2015-04-22 CN claimed
EP-3643735-B1 PHOTOCHROMIC POLYROTAXANE COMPOUND, AND CURABLE COMPOSITION CONTAINING SAID PHOTOCHROMIC POLYROTAXANE COMPOUND TOKUYAMA CORP (JP) 2024-07-31 EP disclosed
EP-3779531-B1 PHOTOCHROMIC OPTICAL ARTICLE AND METHOD FOR MANUFACTURING SAME TOKUYAMA CORP (JP) 2024-03-20 EP disclosed
US-11767467-B2 Photochromic compound and curable composition containing said photochromic compound TOKUYAMA CORPORATION (JP) 2023-09-26 US disclosed
EP-3345954-B1 POLYROTAXANE, PRODUCTION METHOD THEREFOR, AND OPTICAL COMPOSITION CONTAINING SAID POLYROTAXANE TOKUYAMA CORP (JP) 2023-07-05 EP disclosed
US-20230120549-A1 Polyurethanes, Articles and Coatings Prepared Therefrom and Methods of Making the Same PPG INDUSTRIES OHIO, INC. 2023-04-20 US disclosed
EP-3653615-B1 CHROMENE COMPOUND, CURABLE COMPOSITION COMPRISING SAME, AND OPTICAL ARTICLE COMPRISING CURED PRODUCT FORMED OF CURABLE COMPOSITION TOKUYAMA CORP (JP) 2023-03-01 EP disclosed
US-11578174-B2 Polyrotaxane, production method therefor, and optical composition containing said polyrotaxane TOKUYAMA CORPORATION (JP) 2023-02-14 US disclosed
US-11472912-B2 Polyurethanes, articles and coatings prepared therefrom and methods of making the same PPG INDUSTRIES OHIO, INC. (US) 2022-10-18 US disclosed
EP-0378895-B1 A MERCAPTO COMPOUND, A HIGH REFRACTIVE INDEX RESIN AND LENS AND A PROCESS FOR PREPARING THEM MITSUI TOATSU CHEMICALS, Inc. (JP) 1993-07-14 EP disclosed
US-5191055-A Polythiourethanes MITSUI TOATSU CHEMICALS, INC. (JP) 1993-03-02 US disclosed
EP-0528590-A1 Mercapto compound, its preparation process, and sulfur-containing urethane resins and lenses using the same MITSUI TOATSU CHEMICALS, Inc. (JP) 1993-02-24 EP disclosed
US-5087758-A Polythiourethane monomer MITSUI TOATSU CHEMICALS, INC. (JP) 1992-02-11 US disclosed
US-5084545-A Polythiourethanes for impact strength, lightweight lenses MITSUI TOATSU CHEMICALS, INC. (JP) 1992-01-28 US disclosed
EP-0378895-A1 A mercapto compound, a high refractive index resin and lens and a process for preparing them MITSUI TOATSU CHEMICALS, Inc. (JP) 1990-07-25 EP disclosed
EP-0351073-A2 Lens comprising a resin having a large refractive index and process for preparing the lens MITSUI TOATSU CHEMICALS, Inc. (JP) 1990-01-17 EP disclosed
US-4450159-A ORGAN TRANSPLANTS; IMMUNOLOGY THE UPJOHN COMPANY (US) 1984-05-22 US disclosed
US-4352929-A ANTIBODY INHIBITORS THE UPJOHN COMPANY (US) 1982-10-05 US disclosed