SCHEMBL4838616

SCHEMBL4838616

CN(CCOC(=O)c1ccccc1)Cc1ccccc1

nearest known ligand 0.97

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 1/20 0.97
ALDH1A1 P00352 2/20 0.70
LMNA P02545 1/20 0.56
TDP1 Q9NUW8 3/20 0.54
POLB P06746 1/20 0.53
GAA P10253 1/20 0.53
MAPT P10636 1/20 0.53
PKM P14618 1/20 0.53
RECQL P46063 1/20 0.53
CACNA1B Q00975 1/20 0.53
APBA1 Q02410 1/20 0.53
L3MBTL1 Q9Y468 1/20 0.53
KMT2A Q03164 2/20 0.53
SLC6A2 P23975 1/20 0.53
SLC6A3 Q01959 1/20 0.53
ACHE P22303 1/20 0.52
MEN1 O00255 1/20 0.51
ATM Q13315 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16088842 0.91 SMN1; SMN2 (0.82) SMN1; SMN2ALDH1A1TDP1POLBGAA
SCHEMBL16088849 0.90 SMN1; SMN2 (0.80) SMN1; SMN2ALDH1A1TDP1POLBGAA
SCHEMBL1665202 0.84 SMN1; SMN2 (0.70) SMN1; SMN2ALDH1A1TDP1POLBGAA
SCHEMBL3345807 0.83 SMN1; SMN2 (0.68) SMN1; SMN2ALDH1A1LMNATDP1POLB
SCHEMBL10386875 0.83 SMN1; SMN2 (0.68) SMN1; SMN2ALDH1A1TDP1POLBGAA
SCHEMBL8119191 0.82 SMN1; SMN2 (0.67) SMN1; SMN2ALDH1A1LMNATDP1POLB
Hydrochloric Acid SCHEMBL29797126 0.82 SMN1; SMN2 (0.70) SMN1; SMN2ALDH1A1LMNATDP1POLB
SCHEMBL65544 0.82 PHLPP2 (0.70) SMN1; SMN2ALDH1A1LMNATDP1GAA
SCHEMBL16088846 0.81 SMN1; SMN2 (0.67) SMN1; SMN2ALDH1A1TDP1POLBGAA
SCHEMBL16088847 0.81 SMN1; SMN2 (0.67) SMN1; SMN2ALDH1A1TDP1POLBGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2008014505-A2 BLENDS FOR IMPROVED SOLUBILIZATION OF ACTIVE AND FUNCTIONAL ORGANIC COMPOUNDS ISP INVESTMENTS INC. (US) 2008-01-31 WO claimed
US-9464283-B2 Signaling compositions, methods, and systems for effecting plant growth and crop enhancement KamTec, LLC (US) 2016-10-11 US disclosed
US-8999890-B2 Signaling compositions, methods, and systems for effecting plant burndown and herbicide enhancement KamTec, LLC (US) 2015-04-07 US disclosed
WO-2014152496-A1 SIGNALING COMPOSITIONS, METHODS, AND SYSTEMS FOR EFFECTING PLANT GROWTH AND BURNDOWN, AND ENHANCEMENT OF CROPS AND HERBICIDES KamTec, LLC (US) 2014-09-25 WO disclosed
US-20140283198-A1 Signaling Compositions, Methods, and Systems for Effecting Plant Growth and Crop Enhancement KamTec, LLC (US) 2014-09-18 US disclosed
US-20140283199-A1 Signaling Compositions, Methods, and Systems for Effecting Plant Burndown and Herbicide Enhancement KamTec (US) 2014-09-18 US disclosed
US-20050152858-A1 Solubilizing agents for active or functional organic compounds ISP INVESTMENTS INC. 2005-07-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050152858-A1 Solubilizing agents for active or functional organic compounds MITF, TYR, MMS19 SMN1; SMN2 3649/4885ALDH1A1 1259/4885LMNA 2671/4885
US-20140283199-A1 Signaling Compositions, Methods, and Systems for Effecting Plant Burndown and Herbicide Enhancement BOLA2; BOLA2B, DBNL, EBPL SMN1; SMN2 4790/4885ALDH1A1 3134/4885LMNA 3990/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.