SCHEMBL483870

SCHEMBL483870

S=C=Nc1ccc(SSc2ccc(N=C=S)cc2)cc1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MIF P14174 1/20 0.54
P2RY6 Q15077 3/20 0.54
HSD17B10 Q99714 5/20 0.53
CA1 P00915 2/20 0.47
CA2 P00918 2/20 0.47
PNMT P11086 1/20 0.35
HPGD P15428 4/20 0.34
MAPT P10636 3/20 0.34
ALDH1A1 P00352 3/20 0.34
CYP3A4 P08684 3/20 0.34
TDP1 Q9NUW8 3/20 0.34
KDM4E B2RXH2 2/20 0.34
USP2 O75604 2/20 0.34
LTA P01374 2/20 0.34
P2RX3 P56373 2/20 0.34
RAD51 Q06609 2/20 0.34
RAD1 O60671 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.33
MGLL Q99685 1/20 0.33
MEN1 O00255 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Isothiocyanate SCHEMBL26618284 0.93 HSD17B10 (0.49) MIFP2RY6HSD17B10CA1CA2
SCHEMBL484042 0.85 MIF (0.54) MIFP2RY6HSD17B10CA1CA2
Bitoscanate SCHEMBL157128 0.84 MIF (0.72) MIFP2RY6HSD17B10CA1CA2
SCHEMBL1021082 0.81 P2RY6 (0.50) MIFP2RY6HSD17B10CA1CA2
SCHEMBL28766783 0.81 P2RY6 (0.50) MIFP2RY6HSD17B10CA1CA2
SCHEMBL5954570 0.78 MIF (0.64) MIFP2RY6HSD17B10CA1CA2
SCHEMBL729077 0.78 HSD17B10 (0.47) MIFP2RY6HSD17B10CA1CA2
SCHEMBL28944560 0.78 MIF (0.42) MIFP2RY6HSD17B10CA1CA2
SCHEMBL10622884 0.76 MAOA (0.47) MIFP2RY6HSD17B10CA1CA2
SCHEMBL10622868 0.76 HSD17B10 (0.46) MIFP2RY6HSD17B10CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 327 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4748866-A1 AQUEOUS POLYURETHANE DISPERSIONS AND APPLICATIONS THEREOF Covestro Deutschland AG (DE) 2026-05-27 EP disclosed
EP-4396248-B1 AQUEOUS POLYURETHANE-UREA DISPERSION COVESTRO DEUTSCHLAND AG (DE) 2025-08-06 EP disclosed
EP-3841141-B1 A COMPOSITION, PREPARATION METHOD AND APPLICATION THEREOF COVESTRO DEUTSCHLAND AG (DE) 2025-01-01 EP disclosed
US-20240368425-A1 Aqueous Polyurethane-Urea Dispersion COVESTRO DEUTSCHLAND AG (DE) 2024-11-07 US disclosed
EP-3643735-B1 PHOTOCHROMIC POLYROTAXANE COMPOUND, AND CURABLE COMPOSITION CONTAINING SAID PHOTOCHROMIC POLYROTAXANE COMPOUND TOKUYAMA CORP (JP) 2024-07-31 EP disclosed
EP-4396248-A1 AQUEOUS POLYURETHANE-UREA DISPERSION Covestro Deutschland AG (DE) 2024-07-10 EP disclosed
US-11965092-B2 Polyurethane composition, preparation method and application thereof COVESTRO INTELLECTUAL PROPERTY GMBH & CO. KG (DE) 2024-04-23 US disclosed
US-11965108-B2 Composition, preparation method and application thereof COVESTRO INTELLECTUAL PROPERTY GMBH & CO. KG (DE) 2024-04-23 US disclosed
WO-2024080384-A1 POLYTHIOL COMPOSITION, POLYMERIZABLE COMPOSITION, RESIN, MOLDED BODY, OPTICAL MATERIAL, AND LENS 三井化学株式会社 2024-04-18 WO disclosed
CN-117897424-A Aqueous polyurethane urea dispersions 科思创德国股份有限公司 2024-04-16 CN disclosed
EP-0676429-A2 Composition for urethane-base plastic lens MITSUI TOATSU CHEMICALS, INCORPORATED (JP) 1995-10-11 EP disclosed
US-5389708-A Polymerizing polyisocyanate or polyisothiocyanate with polyol or polythiol in presence of thiophosphoric or dithiophosphoric acid ester MITSUI TOATSU CHEMICALS, INC. (JP) 1995-02-14 US disclosed
EP-0630927-A2 Optical urethane resin Takeda Chemical Industries, Ltd. (JP) 1994-12-28 EP disclosed
US-5352758-A Polythiourethane formed by reaction of specific mercaptan with polyisocyanate or polyisothiocyanate MITSUI TOATSU CHEMICALS, INCORPORATED (JP) 1994-10-04 US disclosed
EP-0351073-B1 Lens comprising a resin having a large refractive index and process for preparing the lens MITSUI TOATSU CHEMICALS (JP) 1994-09-21 EP disclosed
US-5283312-A Colorless, transparent, high refractive index, heat resistance, low dispersion; polythiourethanes MITSUI TOATSU CHEMICALS, INC. (JP) 1994-02-01 US disclosed
EP-0553801-A1 Use of sulfur-containing acid phosphoric ester as internal release agent MITSUI TOATSU CHEMICALS, Inc. (JP) 1993-08-04 EP disclosed
EP-0528590-A1 Mercapto compound, its preparation process, and sulfur-containing urethane resins and lenses using the same MITSUI TOATSU CHEMICALS, Inc. (JP) 1993-02-24 EP disclosed
US-5084545-A Polythiourethanes for impact strength, lightweight lenses MITSUI TOATSU CHEMICALS, INC. (JP) 1992-01-28 US disclosed
EP-0351073-A2 Lens comprising a resin having a large refractive index and process for preparing the lens MITSUI TOATSU CHEMICALS, Inc. (JP) 1990-01-17 EP disclosed