Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 4/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL166977 | 0.96 | TP53 (0.40) | TP53ALDH1A1SMN1; SMN2CYP3A4MAPK1 | |
| SCHEMBL536194 | 0.90 | SMN1; SMN2 (0.39) | TP53ALDH1A1SMN1; SMN2MAPTPOLB | |
| SCHEMBL3693328 | 0.90 | SMN1; SMN2 (0.36) | TP53ALDH1A1SMN1; SMN2CYP3A4MAPK1 | |
| SCHEMBL19203369 | 0.89 | TP53 (0.35) | TP53ALDH1A1SMN1; SMN2CYP3A4MAPK1 | |
| SCHEMBL20017398 | 0.85 | TP53 (0.37) | TP53ALDH1A1SMN1; SMN2CYP3A4MAPK1 | |
| SCHEMBL169015 | 0.84 | PKM (0.39) | TP53ALDH1A1SMN1; SMN2MAPTL3MBTL1 | |
| SCHEMBL19196174 | 0.82 | TP53 (0.33) | TP53ALDH1A1SMN1; SMN2CYP3A4MAPK1 | |
| SCHEMBL10028722 | 0.82 | TP53 (0.33) | TP53ALDH1A1SMN1; SMN2CYP3A4MAPK1 | |
| SCHEMBL9571740 | 0.82 | SMN1; SMN2 (0.34) | TP53ALDH1A1SMN1; SMN2MAPTPOLB | |
| SCHEMBL19447732 | 0.81 | SMN1; SMN2 (0.33) | TP53ALDH1A1SMN1; SMN2MAPTPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7452952-B2 | Method of applying removable coating compositions | ROHM AND HAAS COMPANY (US) | 2008-11-18 | — | — | US | disclosed |
| US-7396891-B2 | Two-component coating composition and method of preparation | ROHM AND HAAS COMPANY (US) | 2008-07-08 | — | — | US | disclosed |
| US-7230060-B2 | Removable coating compositions | ROHM AND HAAS COMPANY (US) | 2007-06-12 | — | — | US | disclosed |
| US-20070098915-A1 | Method of applying removable coating compositions | KOHR ALAN W | 2007-05-03 | — | — | US | disclosed |
| US-20050137335-A1 | Two-component coating composition and method of preparation | GRAY RICHARD T (US) | 2005-06-23 | — | — | US | disclosed |
| US-6875834-B2 | Two-component coating composition and method of preparation | ROHM AND HAAS COMPANY (US) | 2005-04-05 | — | — | US | disclosed |
| US-6855403-B2 | Applying to a substrate, a first-coating composition that is removable, followed by application of a second-coating composition that is highly durable but not readily removable. | ROHN AND HAAS COMPANY (US) | 2005-02-15 | — | — | US | disclosed |
| US-20040138327-A1 | Compositions having a plurality of triggered responses | KOHR ALAN WAYNE (US) | 2004-07-15 | — | — | US | disclosed |
| US-20040138328-A1 | Multistage polymer emulsion; radiation curable; strippable | ROHM AND HAAS COMPANY | 2004-07-15 | — | — | US | disclosed |
| EP-1431355-A1 | COATING COMPOSITIONS HAVING A PLURALITY OF TRIGGERED RESPONSES | ROHM AND HAAS COMPANY (US) | 2004-06-23 | — | — | EP | disclosed |
| EP-1431324-A2 | Removable coating compositions | ROHM AND HAAS COMPANY (US) | 2004-06-23 | — | — | EP | disclosed |
| EP-0881247-B1 | Crosslinked poly (amino acids) and method of preparation thereof | ROHM & HAAS (US) | 2004-02-11 | — | — | EP | disclosed |
| US-20030224195-A1 | Multi-layer coating composition and method of preparation | ROHM AND HAAS COMPANY | 2003-12-04 | — | — | US | disclosed |
| EP-1366828-A1 | Multi-layer coating composition and method of preparation | ROHM AND HAAS COMPANY (US) | 2003-12-03 | — | — | EP | disclosed |
| US-20020183455-A1 | Two-component coating composition and method of preparation | ROHM AND HAAS COMPANY | 2002-12-05 | — | — | US | disclosed |
| EP-1227116-A1 | Two-component coating composition and method of preparation | ROHM AND HAAS COMPANY (US) | 2002-07-31 | — | — | EP | disclosed |