Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC8 | Q9BY41 | 4/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL483981 | 1.00 | HDAC8 (0.34) | HDAC8 | |
| Hydrochloric Acid SCHEMBL1151784 | 0.98 | HDAC8 (0.33) | HDAC8 | |
| Hydrochloric Acid SCHEMBL1151781 | 0.98 | HDAC8 (0.33) | HDAC8 | |
| SCHEMBL5196485 | 0.81 | HDAC8 (0.32) | HDAC8 | |
| Hydrochloric Acid SCHEMBL4805084 | 0.80 | HDAC8 (0.31) | HDAC8 | |
| SCHEMBL5197895 | 0.79 | KDM4E (0.45) | HDAC8 | |
| Hydrochloric Acid SCHEMBL4799280 | 0.78 | KDM4E (0.44) | — | |
| SCHEMBL839888 | 0.72 | HDAC8 (0.33) | HDAC8 | |
| Hydrochloric Acid SCHEMBL1152353 | 0.71 | HDAC8 (0.33) | HDAC8 | |
| Hydrochloric Acid SCHEMBL1152348 | 0.71 | HDAC8 (0.33) | HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2248515-B1 | Use for dying keratinic fibers of a azomethine-type compound having a pyrazolopyridine group | ORÉAL L (FR) | 2015-12-23 | — | — | EP | disclosed |
| EP-2246038-B1 | Azomethinic cationic pyrazolidine derivatives for dyeing keratin fiber | ORÉAL L (FR) | 2014-10-22 | — | — | EP | disclosed |
| EP-1859784-B1 | Use of a cationic hydrotrope for direct dyeing of keratin fibres, composition containing it and hair dyeing method | OREAL (FR) | 2013-01-16 | — | — | EP | disclosed |
| EP-2010494-B1 | SPECIFIC MONOCATIONIC MONOCHROMOPHORIC COMPOUNDS OF HYDRAZONE TYPE COMPRISING A 2-, 4-PYRIDINIUM OR 2-, 4-QUINOLINIUM UNIT, SYNTHESIS THEREOF, DYE COMPOSITIONS CONTAINING THEM, AND METHOD FOR DYEING KERATIN FIBRES | OREAL (FR) | 2012-02-01 | — | — | EP | disclosed |
| EP-2248515-A1 | Use for dying keratinic fibers of a azomethine-type compound having a pyrazolopyridine group | L'Oréal (FR) | 2010-11-10 | — | — | EP | disclosed |
| EP-2246038-A1 | Azomethinic cationic pyrazolidine derivatives for dyeing keratin fiber | L'Oréal (FR) | 2010-11-03 | — | — | EP | disclosed |
| EP-2011787-A1 | Dying composition comprising an azomethin-type compound with a pyrazolinone moiety | L'Oreal (FR) | 2009-01-07 | — | — | EP | disclosed |
| EP-2010494-A1 | SPECIFIC MONOCATIONIC MONOCHROMOPHORIC COMPOUNDS OF HYDRAZONE TYPE COMPRISING A 2-, 4-PYRIDINIUM OR 2-, 4-QUINOLINIUM UNIT, SYNTHESIS THEREOF, DYE COMPOSITIONS CONTAINING THEM, AND METHOD FOR DYEING KERATIN FIBRES | L'Oréal (FR) | 2009-01-07 | — | — | EP | disclosed |
| EP-1980558-A1 | Polycationic monochromophoric compounds of hydrazone type, dyeing compositions comprising same and dyeing method | L'Oréal (FR) | 2008-10-15 | — | — | EP | disclosed |
| EP-1859784-A1 | Use of a cationic hydrotrope for direct dyeing of keratin fibres, composition containing it and hair dyeing method | L'Oréal (FR) | 2007-11-28 | — | — | EP | disclosed |
| EP-1859778-A1 | Use of an anionic hydrotrope for dyeing of keratin fibres, compositions containing them and hair dyeing methods | L'Oréal (FR) | 2007-11-28 | — | — | EP | disclosed |
| WO-2007125238-A1 | SPECIFIC MONOCATIONIC MONOCHROMOPHORIC COMPOUNDS OF HYDRAZONE TYPE COMPRISING A 2-, 4-PYRIDINIUM OR 2-, 4-QUINOLINIUM UNIT, SYNTHESIS THEREOF, DYE COMPOSITIONS CONTAINING THEM, AND METHOD FOR DYEING KERATIN FIBRES | L'ORÉAL (FR) | 2007-11-08 | — | — | WO | disclosed |
| WO-2007122340-A1 | CATIONIC DICHROMOPHORIC COMPOUND CONTAINING TWO UNITS OF HYDRAZONE TYPE AND COMPRISING A CATIONIC LINKER ARM, DYE COMPOSITION COMPRISING AT LEAST ONE SUCH COMPOUND, METHOD FOR THE USE THEREOF AND USES | L'ORÉAL (FR) | 2007-11-01 | — | — | WO | disclosed |
| WO-2007122341-A2 | SPECIFIC MONOCATIONIC MONOCHROMOPHORIC HYDRAZONE COMPOUNDS CONTAINING A 2-(BENZ)IMIDAZOLIUM UNIT, THEIR SYNTHESIS, DYEING COMPOSITIONS COMPRISING THEM, METHOD OF DYEING KERATIN FIBRES | L'ORÉAL (FR) | 2007-11-01 | — | — | WO | disclosed |